A0A443WK86 · A0A443WK86_9ENTR

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site114L-glutamate (UniProtKB | ChEBI)
Active site391Nucleophile
Binding site409-411L-glutamate (UniProtKB | ChEBI)
Binding site433L-glutamate (UniProtKB | ChEBI)
Binding site462-463L-glutamate (UniProtKB | ChEBI)
Binding site484L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione biosynthetic process
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • ORF names
      DN619_11545

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • GEO_33_Up_A
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella

Accessions

  • Primary accession
    A0A443WK86

Proteomes

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-25
ChainPRO_501945035426-580Glutathione hydrolase proenzyme

Post-translational modification

Cleaved by autocatalysis into a large and a small subunit.

Keywords

Interaction

Subunit

This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region558-580Disordered

Sequence similarities

Belongs to the gamma-glutamyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    580
  • Mass (Da)
    61,819
  • Last updated
    2019-05-08 v1
  • Checksum
    0AECF440C3032696
MIKTTLWRQVIIAALLAGGSFTVAADPAPPPVSYGVEEDVFHPVRAQQGMVASVDALATKVGVDILRQGGNAVDAAVVVGYALAVTHPQAGNIGGGGFMMLRTKDGNTTAIDFREMAPEQATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALEKYGTMPLNKVIRPAIKLAEEGFTVNDALADDLKTYGSEVIPDHANSRAIFWKNGEPLKKGDKLVQKQLGKSLELIAELGPDAFYKGAIADQIAAEMKNNGGLITKADLANYKAVERTPVSGEYRGYQVFSMPPPSSGGIHIVQILNILENFDMHKYGFGSADAMQVMAEAEKHAYADRSEYLGDPDFVKVPWQALTSKAYAKSIAEQIDINKAKPSSQIRPGKLAPYESNQTTHFSVVDKDGNAVAVTYTLNTTFGTGIVAGNSGILLNNQMDDFSAKPGVPNVYGLVGGDANAVEPKKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNTIDFGMNVAEATNAPRFHHQWLPDELRVEKGFSPDTLKLLESKGQKVAVKEAMGSTQSIMVGPDGTLYGASDPRSPDDLTAGY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QKPB01000018
EMBL· GenBank· DDBJ
RWT45353.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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