A0A443W1Q0 · A0A443W1Q0_AERCA
- ProteinBeta-galactosidase
- GenelacZ_2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1020 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 magnesium ions per monomer.
Note: Binds 1 sodium ion per monomer.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 106 | substrate | ||||
Sequence: N | ||||||
Binding site | 205 | Na+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 205 | substrate | ||||
Sequence: D | ||||||
Site | 359 | Transition state stabilizer | ||||
Sequence: H | ||||||
Site | 393 | Transition state stabilizer | ||||
Sequence: H | ||||||
Binding site | 418 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 420 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Active site | 463 | Proton donor | ||||
Sequence: E | ||||||
Binding site | 463 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 463 | substrate | ||||
Sequence: E | ||||||
Active site | 539 | Nucleophile | ||||
Sequence: E | ||||||
Binding site | 539-542 | substrate | ||||
Sequence: EYAH | ||||||
Binding site | 599 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 603 | Na+ (UniProtKB | ChEBI) | ||||
Sequence: F | ||||||
Binding site | 606 | Na+ (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 606 | substrate | ||||
Sequence: N | ||||||
Binding site | 998 | substrate | ||||
Sequence: W |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | beta-galactosidase complex | |
Molecular Function | beta-galactosidase activity | |
Molecular Function | carbohydrate binding | |
Molecular Function | magnesium ion binding | |
Biological Process | lactose catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBeta-galactosidase
- EC number
- Short namesBeta-gal
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Aeromonadales > Aeromonadaceae > Aeromonas
Accessions
- Primary accessionA0A443W1Q0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 751-1020 | Beta galactosidase small chain/ | ||||
Sequence: RITAANSQWRLDKQSGRITSWQKSGKEQLLAPIMDHFYRAPLDNDIGTSEADHADPNSWIARWQACGLGQWQHRCLGISVTGGDIRVSHGYFHHDELLLVSHWHHCFTDDGAMSLEIETELAQALPSLPRIGLLLHLAEVPVRAEWLGRGPHENYPDRLLGADLGHWSLPLEAMHTPYIFPSDNGLRCDTRQLQLGSTTVNGSFHFSASRFSQQQLAAARHQSDLVAEEGLWVCLDGAHMGVGGDDSWSQSVRPEYQLLGRSYRWGCTLY |
Sequence similarities
Belongs to the glycosyl hydrolase 2 family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,020
- Mass (Da)115,112
- Last updated2019-05-08 v1
- ChecksumD2D61380CF5310FC
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BPNQ01000070 EMBL· GenBank· DDBJ | GJA77908.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAOCIZ010000032 EMBL· GenBank· DDBJ | MDH1505350.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAOCJV010000001 EMBL· GenBank· DDBJ | MDH1995209.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAAVMO010000023 EMBL· GenBank· DDBJ | NKD18592.1 EMBL· GenBank· DDBJ | Genomic DNA |