A0A443W1Q0 · A0A443W1Q0_AERCA

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.
    EC:3.2.1.23 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.
Na+ (UniProtKB | Rhea| CHEBI:29101 )

Note: Binds 1 sodium ion per monomer.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site106substrate
Binding site205Na+ (UniProtKB | ChEBI)
Binding site205substrate
Site359Transition state stabilizer
Site393Transition state stabilizer
Binding site418Mg2+ 1 (UniProtKB | ChEBI)
Binding site420Mg2+ 1 (UniProtKB | ChEBI)
Active site463Proton donor
Binding site463Mg2+ 1 (UniProtKB | ChEBI)
Binding site463substrate
Active site539Nucleophile
Binding site539-542substrate
Binding site599Mg2+ 2 (UniProtKB | ChEBI)
Binding site603Na+ (UniProtKB | ChEBI)
Binding site606Na+ (UniProtKB | ChEBI)
Binding site606substrate
Binding site998substrate

GO annotations

AspectTerm
Cellular Componentbeta-galactosidase complex
Molecular Functionbeta-galactosidase activity
Molecular Functioncarbohydrate binding
Molecular Functionmagnesium ion binding
Biological Processlactose catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Beta-galactosidase
  • EC number
  • Short names
    Beta-gal
  • Alternative names
    • Lactase

Gene names

    • Name
      lacZ_2
    • Synonyms
      lacZ
    • ORF names
      HED45_21340
      , KAM354_31440
      , N5I20_09790
      , N5J40_10430

Organism names

  • Taxonomic identifier
  • Strains
    • UFMG-H8
    • KAM354
    • GD03687
    • GD03710
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Aeromonadales > Aeromonadaceae > Aeromonas

Accessions

  • Primary accession
    A0A443W1Q0

Proteomes

Subcellular Location

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain751-1020Beta galactosidase small chain/

Sequence similarities

Belongs to the glycosyl hydrolase 2 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,020
  • Mass (Da)
    115,112
  • Last updated
    2019-05-08 v1
  • Checksum
    D2D61380CF5310FC
MTLQQIIYRADWQTQAVTSVNRLPAHTPMFSWRSETDARGDLASSSRLLLDGEWRFSFFAAPELVPESWLAQDLVDACPITVPGNWQLDAAYPAARPLTDGPIYTNIKYPFPCDPPRVPAENPTGCYSREFELPADWLASGQSRIIFDGVSSAFHLFCNGRWVGYSQDSRLPAEFDLTPYLQSGRNRLAVLVLRWSDGSYLEDQDMWWLSGIFRSVSLLHKPSRHLMDMRVTPELDACYRDGRLKIALQVANGAGLSVEANLYDGSERVATLLQLIGTQAIDEKGAYDDRAELWLDVAAPRKWSAETPHLYRFTLTLLDEQGQAIESEACDVGFRVVEIRGGLLRVNGQPLLIRGANRHEHHPAKGYAIDRATMERDLLLMKRHNFNAVRCSHYPNHPDFYRLCDRLGLYVVDEANLETHGMTPMGRLARDPAWSNAFLERATRMVARDFNHPSIIIWSLGNESGYGPAHDAMYGWIKRSDPSRPVQYEGGGADTPATDIICPMYARTHQDQPFPAVTKWALAKWIGLPDEHRPLILCEYAHAMGNSLGGYAHYWQAFRDHPRLQGGFVWDWVDQGLDKYTADGRHYWGYGGDFGDVQNDRQFCCNGLLFPDRTPHPALCEAKRAQQPFRFTLLEHIPLRVRIESEYLFRETDNERLCWQLCENGHVQQQGEISLELAPQGVVELTLSETLPTFAAGSQAWLDLAIIQPQATLWSQADHKVARQQFTLPTPLSLPAPAAVAILTEQPDGWRITAANSQWRLDKQSGRITSWQKSGKEQLLAPIMDHFYRAPLDNDIGTSEADHADPNSWIARWQACGLGQWQHRCLGISVTGGDIRVSHGYFHHDELLLVSHWHHCFTDDGAMSLEIETELAQALPSLPRIGLLLHLAEVPVRAEWLGRGPHENYPDRLLGADLGHWSLPLEAMHTPYIFPSDNGLRCDTRQLQLGSTTVNGSFHFSASRFSQQQLAAARHQSDLVAEEGLWVCLDGAHMGVGGDDSWSQSVRPEYQLLGRSYRWGCTLY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BPNQ01000070
EMBL· GenBank· DDBJ
GJA77908.1
EMBL· GenBank· DDBJ
Genomic DNA
JAOCIZ010000032
EMBL· GenBank· DDBJ
MDH1505350.1
EMBL· GenBank· DDBJ
Genomic DNA
JAOCJV010000001
EMBL· GenBank· DDBJ
MDH1995209.1
EMBL· GenBank· DDBJ
Genomic DNA
JAAVMO010000023
EMBL· GenBank· DDBJ
NKD18592.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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