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A0A438N5I2 · A0A438N5I2_EXOME

Function

function

S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

159050100150200250300350400450500550
TypeIDPosition(s)Description
Binding site59S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site86-88S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site108S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site140S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site164S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionhydrolase activity, hydrolyzing O-glycosyl compounds
Molecular FunctionN-terminal protein N-methyltransferase activity
Molecular Functionprotein-lysine N-methyltransferase activity
Biological Processcarbohydrate metabolic process
Biological ProcessN-terminal peptidyl-glycine methylation
Biological Processpeptidyl-lysine dimethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein N-terminal and lysine N-methyltransferase EFM7
  • EC number
  • Alternative names
    • Elongation factor methyltransferase 7

Gene names

    • Name
      EFM7
    • ORF names
      B0A52_06137

Organism names

  • Taxonomic identifier
  • Strain
    • CCFEE 6314
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Chaetothyriomycetidae > Chaetothyriales > Herpotrichiellaceae > Exophiala

Accessions

  • Primary accession
    A0A438N5I2

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-25Disordered
Region269-331Disordered
Compositional bias276-312Polar residues
Domain352-587GH16
Region488-509Disordered

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    590
  • Mass (Da)
    65,713
  • Last updated
    2019-05-08 v1
  • MD5 Checksum
    31E31F21059D4FBCE0108169ED5DB2FB
MGDESSSDDEPASAALFNEPEGYYQPEKPATFTNYTLTNGRHFNLRLVGHSPLWGHLLWNAGQVVAQYLEENAQSLVKNKTVLELGAGAGLPSLVSATLGAKQVVVTDYPESDLISNLQYNIQHNLTEADSPISAHGFLWGAPAQGLKDKLSPDADEFHLLILADILFNHSEHDKLLATLGDCLAKSNDAVALVFFTPYRPWLLEKDLNFFDIARAAGFAVEQVMEHTMEKVMFENDPGDQQLRRTVFGYTIKWDRIKEVWEDKVIGCFGTPEQDENPDAPSSVPQAPSATAADPTGTYQRSQGSQIPSPGVGVKNDVNAEYRPNRDPGDVQYANGTWIVRDVDTFSNKAVYTFSGDTLPDGLYASDYTVQNRLGDDGPRTGTLYNHRFDPANVQLSNGFVRLIVPSGQRPNRRPDKAISCAEIVTAETNIISASVRTRAVFSKVPGTWMFFYKNDTQEIDIEYLTDPTSLSNNGPREPIPIWYTNQPIDPENPEDHDPTSETGPAPFDCTSRVHEYRIDWTREYTAFYLDGVEQKRFTDNVPSAPGSWVWNNWANGDKGWSKGPPKGTADNVFKIQSIWMYYNTSTETT

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias276-312Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NAJM01000020
EMBL· GenBank· DDBJ
RVX70979.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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