A0A438HEP1 · A0A438HEP1_VITVI
- ProteinHomoserine dehydrogenase
- GeneAKHSDH1_0
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids198 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- L-homoserine + NADP+ = H+ + L-aspartate 4-semialdehyde + NADPHThis reaction proceeds in the backward direction.
Cofactor
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | homoserine dehydrogenase activity | |
Molecular Function | kinase activity | |
Molecular Function | NADP binding | |
Biological Process | isoleucine biosynthetic process | |
Biological Process | methionine biosynthetic process | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomoserine dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > Vitales > Vitaceae > Viteae > Vitis
Accessions
- Primary accessionA0A438HEP1
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 31-118 | Aspartate/homoserine dehydrogenase NAD-binding | ||||
Sequence: RWRELIKEKGEVGDMHKFVNHVHGNHFIPNTALVDCTADSNVASHYHEWLRKGIHVITPNKKANSGPLDQYLKLRALQRQSYTHYFYE | ||||||
Domain | 126-195 | Homoserine dehydrogenase catalytic | ||||
Sequence: PIISTLRGLLETGDKILRIEGIFSGTLSYIFNNFKGTRRFSEVVMEAKQAGYTEPDPRDDLSGTDVARKV |
Sequence similarities
Belongs to the homoserine dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length198
- Mass (Da)22,483
- Last updated2019-05-08 v1
- ChecksumFF4F440780A1D846