A0A437C1U2 · A0A437C1U2_ORYJA
- ProteinProtein smoothened
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids821 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameProtein smoothened
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Atherinomorphae > Beloniformes > Adrianichthyidae > Oryziinae > Oryzias
Accessions
- Primary accessionA0A437C1U2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-32 | Helical | ||||
Sequence: VYGMLCAWAAWLSGCGAALAP | ||||||
Transmembrane | 208-229 | Helical | ||||
Sequence: YIAYFGTITLLCTFFTLATFLA | ||||||
Transmembrane | 241-261 | Helical | ||||
Sequence: ILFYINACFFVGSIGWLAQFL | ||||||
Transmembrane | 286-314 | Helical | ||||
Sequence: TLSCVTIFIIVYYSLMSGVIWFVMLTYAW | ||||||
Transmembrane | 334-356 | Helical | ||||
Sequence: YFHMVTWSVPFVLTVAILAIAEV | ||||||
Transmembrane | 377-404 | Helical | ||||
Sequence: GFVLAPIGVVLLVGGYFLIRGVMTLFSI | ||||||
Transmembrane | 424-450 | Helical | ||||
Sequence: MLRLGIFGFLAFGFVFITFGCHFYDFF | ||||||
Transmembrane | 495-513 | Helical | ||||
Sequence: INLFSMFGTGIAMSTWVWT |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 42-156 | FZ | ||||
Sequence: KKTTTCEVLKYNTCLGSPLPYSHTSLILAEDSSSQEEVFEKLTMWSGLRNAPRCWSVIQPLLCAVYMPKCENGRVELPSQSLCLATRRPCSIVDQERGWPAFLKCDQFPVGCSNE | ||||||
Domain | 205-468 | G-protein coupled receptors family 2 profile 2 | ||||
Sequence: MHAYIAYFGTITLLCTFFTLATFLADWKNSNRYPAVILFYINACFFVGSIGWLAQFLDGARKEIVCKSDNTMRLGEPSSSETLSCVTIFIIVYYSLMSGVIWFVMLTYAWHTSFKALGTTHQPLSGRTSYFHMVTWSVPFVLTVAILAIAEVDGDSVSGICFVGYKNYRYRAGFVLAPIGVVLLVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVFITFGCHFYDFFNQAEWEKSFREYVLCEAN | ||||||
Region | 642-711 | Disordered | ||||
Sequence: IKRKKKKKKKRRKEVRPDEEVADRQPYPQREFGRSSVPRLPKLPCNSSLVGNHHRQQRQQKMEEEVLPGS | ||||||
Compositional bias | 654-668 | Basic and acidic residues | ||||
Sequence: KEVRPDEEVADRQPY |
Sequence similarities
Belongs to the G-protein coupled receptor Fz/Smo family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Protein family/group databases
Sequence
- Sequence statusComplete
- Length821
- Mass (Da)92,503
- Last updated2019-05-08 v1
- Checksum413DA40EF362CCF0
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 654-668 | Basic and acidic residues | ||||
Sequence: KEVRPDEEVADRQPY |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM012459 EMBL· GenBank· DDBJ | RVE56718.1 EMBL· GenBank· DDBJ | Genomic DNA |