A0A434ACY2 · A0A434ACY2_9FLAO

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site99Transition state stabilizer
Active site103Proton acceptor
Binding site289Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      D0817_00935

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CCM 8825
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Flavobacterium

Accessions

  • Primary accession
    A0A434ACY2

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link248↔274Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-102)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-30Disordered
Domain136-481Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    758
  • Mass (Da)
    83,470
  • Last updated
    2019-05-08 v1
  • MD5 Checksum
    7054D3A989D8D5D23998B934B8D181FB
MENNSNDISKCPFHNGSTKQATAVNSGTKNQDWWPNQLKVSVLRQHSSLSNPMEEDFNYAESFKTLDLEALKKDLHALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRVGDGRGGAGAGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGRKISWADLMILTGNIALESMGFKTFGFAGGREDVWEPEQDIYWGSEKVWLGGDERYAHGSEGVAKHAVVSSDDNADGDIHTRDLEKPLAAVQMGLIYVNPEGPDGNPDPIAAAKDIRDTFGRMAMNDEETVALIAGGHTFGKTHGAAPSDNVGVEPEGGDLEQQGLGWHNKFGSGKGKDAITSGLEVTWTTTPTQWSNNFFENLFGFEWELSKSPAGAHQWVAKNADAIIPDAFDASKKHLPTMLTTDLSLRLDPEYEKISRRFLENPDQFADAFARAWFKLTHRDMGPRALYLGSDVPAEELLWQDPIPALNHTLVDDGDIRELKSRILNSGLTVAELVATAWASASTFRGSDKRGGANGARIRLAPQKDWTVNNPAQLQKVLVVLEGIQREFNTTQSDTKKVSLADLIVLAGGVGIEKAAREGGNEITVPFTPGRTDALQDQTDVESFSFLEPVADGFRNYKKTKYSVATEALLIDKAQLLTLTAPELTVLVGGMRALNANFDGSAKGIFTNRPQILSNDFFVNLLDMGIAWKAVSEDKEEYAGHDRTTGEVKWTGTRADLVFGSNSELRAIAEVYASADSEAKFVSDFVKAWTKVMNLDRFDLL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QWDM01000001
EMBL· GenBank· DDBJ
RUT72214.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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