A0A432ETK8 · A0A432ETK8_9AQUI

  • Protein
    Thiol:disulfide interchange protein DsbD
  • Gene
    dsbD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionelectron transfer activity
Molecular Functionprotein-disulfide reductase (NAD(P)H) activity
Biological Processcell redox homeostasis
Biological Processcytochrome complex assembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Thiol:disulfide interchange protein DsbD
  • EC number
  • Alternative names
    • Protein-disulfide reductase
      (Disulfide reductase
      )

Gene names

    • Name
      dsbD
    • ORF names
      DSZ29_08255

Organism names

Accessions

  • Primary accession
    A0A432ETK8

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane352-383Helical
Transmembrane395-420Helical
Transmembrane432-454Helical
Transmembrane475-505Helical
Transmembrane511-537Helical
Transmembrane549-566Helical
Transmembrane572-593Helical
Transmembrane605-626Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-25
ChainPRO_501959690626-782Thiol:disulfide interchange protein DsbD
Disulfide bond371↔493Redox-active
Disulfide bond694↔697Redox-active

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain642-779Thioredoxin

Sequence similarities

Belongs to the thioredoxin family. DsbD subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    782
  • Mass (Da)
    84,194
  • Last updated
    2019-05-08 v1
  • Checksum
    573880C89E8140DE
MKKLLTLLFAFITSIAITSNSYAFGAENLLKPNKAFQVSIESNGPDFITATWEIADGYYMYRKRFSFSSNTADVTLGKPIFPEGELKDDPGFGKVTVYRKRVSIKIPVENPKNISLANIKTKSQGCADIGVCYPPQKVSVDVTLPQAIAKKITTSESITTIGALDTAASNPSDLAAQLGIPSLGKGKKSGGVLPPDEAFAFDINATDKQTLNAHWQITPGHYLYKNKIKFFVRDSNDITLGKLALPKGEKHHDEYFGDIVTYTKDFDIKLPLLGSTGADSVTIKTSYQGCSKITGICYPPQIKTQKIDLRSAQTAIQTVASTSPSSETSSSNSDDKVSEQDQFANILKDNNLFAILGLFFIAGLALTFTPCVFPMIPILSGIISGQGNDISKKKAFILSLAYVIPMALTYAIVGVLAGLSGESLTAALQTPWVIASFAILFVILAFAMFGFYELQMPSSIQNKLSSISNNQKGGTLLGAAIMGMLSALIVGPCVTAPLTGALIFIADTKDALLGGLSLFMLGIGMGVPLLIIGTAAGEFLPKAGAWMDKVKAVFGVLMLGLAIWMLERILPIEIIILLTAALLIGSAIYMKAIDPLDANNSGWDRLWKAVGIIILAYGLILIAGIAKGNKSFIYPLKDKVISQVSTSAAGGTIINATEGLVFSPIKGIKGLNLALDTAATQNKTVMLDFYADWCISCKEMEHKVFSDPRVVKALENTILIQADVTKNDDLDIALMKKFGLFGPPGILFFDTNKQEYRSFRVVGEMSADKFLAHINEFLSQKK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QOAQ01000163
EMBL· GenBank· DDBJ
RTZ62467.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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