A0A432ETK8 · A0A432ETK8_9AQUI
- ProteinThiol:disulfide interchange protein DsbD
- GenedsbD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids782 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.
Catalytic activity
- [protein]-dithiol + NAD+ = [protein]-disulfide + NADH + H+
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | electron transfer activity | |
Molecular Function | protein-disulfide reductase (NAD(P)H) activity | |
Biological Process | cell redox homeostasis | |
Biological Process | cytochrome complex assembly |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThiol:disulfide interchange protein DsbD
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Aquificota > Aquificia > Aquificales > Aquificaceae
Accessions
- Primary accessionA0A432ETK8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 352-383 | Helical | |||
Transmembrane | 395-420 | Helical | |||
Transmembrane | 432-454 | Helical | |||
Transmembrane | 475-505 | Helical | |||
Transmembrane | 511-537 | Helical | |||
Transmembrane | 549-566 | Helical | |||
Transmembrane | 572-593 | Helical | |||
Transmembrane | 605-626 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-25 | ||||
Chain | PRO_5019596906 | 26-782 | Thiol:disulfide interchange protein DsbD | ||
Disulfide bond | 371↔493 | Redox-active | |||
Disulfide bond | 694↔697 | Redox-active | |||
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length782
- Mass (Da)84,194
- Last updated2019-05-08 v1
- Checksum573880C89E8140DE
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QOAQ01000163 EMBL· GenBank· DDBJ | RTZ62467.1 EMBL· GenBank· DDBJ | Genomic DNA |