A0A432EGB0 · A0A432EGB0_9GAMM
- ProteinPeptidoglycan D,D-transpeptidase FtsI
- GeneftsI
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids583 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
Catalytic activity
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 300 | Acyl-ester intermediate | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | penicillin binding | |
Molecular Function | peptidoglycan glycosyltransferase activity | |
Molecular Function | serine-type D-Ala-D-Ala carboxypeptidase activity | |
Biological Process | cell wall organization | |
Biological Process | division septum assembly | |
Biological Process | FtsZ-dependent cytokinesis | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | proteolysis | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptidoglycan D,D-transpeptidase FtsI
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria
Accessions
- Primary accessionA0A432EGB0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Single-pass membrane protein
Membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 21-40 | Helical | ||||
Sequence: RFFALTLVLGIMGLLGLRAF |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 64-213 | Penicillin-binding protein dimerisation | ||||
Sequence: VQPMRGMITDRNGRPLAVSAPVDSVAADPVKLAASPTRFRELEKALGMGRGEIQKKLKRYKGKRFMWLKRQLVPEQAEKVDALNIAGVWLKRDFKRYYPFSYMASHVVGFTGTDNVGLEGLERAYDEALRGVPGKQRVLKDMTGRIIERV | ||||||
Domain | 253-549 | Penicillin-binding protein transpeptidase | ||||
Sequence: GSVVVLDVNTGEILAMANEPGYNPNNRKGVSARAFQNRAVNYTYEPGSTMKTFTILSALSDNLVNAESRIDTSPGYLQIGRFTVHDHTNMGMLTVSLVLKKSSNVGAAKIADRLSNERMWKTLDLAGFGHAPGSGLPGESKGRLPNYSGWKRSEKITMAYGYHIAVTPLQLARAYGVIARGGRQFPVTILKHEEPVDGEQVFDPKKVAQLTRMLEGVVEKGGTAPLAAVDHYQVAGKTGTAHKIKHGAYSKKDYVGSFAGFAPSSHPRLVVAVMIDEPSNGKHFGGDVAGPVFRNVM | ||||||
Region | 560-583 | Disordered | ||||
Sequence: PEIGPDSPSIRRADVRSGGVQHAG |
Sequence similarities
Belongs to the transpeptidase family. FtsI subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length583
- Mass (Da)63,813
- Last updated2019-05-08 v1
- ChecksumC9C23DD9FE13F732