A0A431UR52 · A0A431UR52_STEMA
- ProteinDiacylglycerol kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids131 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
Catalytic activity
- a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+
Cofactor
Note: Mn2+, Zn2+, Cd2+ and Co2+ support activity to lesser extents.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 14 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 14 | substrate | ||||
Sequence: R | ||||||
Binding site | 18-23 | substrate | ||||
Sequence: AARWSW | ||||||
Binding site | 27-30 | substrate | ||||
Sequence: RAAW | ||||||
Binding site | 33 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 33 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 60 | substrate | ||||
Sequence: R | ||||||
Active site | 74 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 74 | substrate | ||||
Sequence: E | ||||||
Binding site | 81 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 81 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 90-92 | ATP (UniProtKB | ChEBI) | ||||
Sequence: EIH | ||||||
Binding site | 99-100 | ATP (UniProtKB | ChEBI) | ||||
Sequence: KD | ||||||
Binding site | 103 | substrate | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent diacylglycerol kinase activity | |
Molecular Function | metal ion binding | |
Biological Process | phosphatidic acid biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDiacylglycerol kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Stenotrophomonas > Stenotrophomonas maltophilia group
Accessions
- Primary accessionA0A431UR52
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 36-55 | Helical | ||||
Sequence: FRLEVYLLILLAPVAIWLGQ | ||||||
Transmembrane | 61-84 | Helical | ||||
Sequence: ALLIGSMLLVLAMELANSAIEAVI | ||||||
Transmembrane | 104-126 | Helical | ||||
Sequence: AAVFVLMMNVLLCWALVVVPHAM |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length131
- Mass (Da)14,512
- Last updated2019-05-08 v1
- Checksum7DA6B0C86CFCCED5