A0A426VVE2 · A0A426VVE2_9BACT

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site74Proton acceptor
Binding site74-75NAD+ (UniProtKB | ChEBI)
Binding site148-149NAD+ (UniProtKB | ChEBI)
Binding site159NAD+ (UniProtKB | ChEBI)
Binding site176NAD+ (UniProtKB | ChEBI)
Binding site178NAD+ (UniProtKB | ChEBI)
Binding site246NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      nadK
    • ORF names
      P794_09975

Organism names

Accessions

  • Primary accession
    A0A426VVE2

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    290
  • Mass (Da)
    32,138
  • Last updated
    2019-05-08 v1
  • Checksum
    6E151F85975EDE81
MSNQKLAQIKTAGFVLKPDTPDIKPLYEKIKAQFEAKGITVILAKQSAEMIDEEGVAFESMCQEADFLVSLGGDGTLLSLVRRSYGYHKPVVGINAGNLGFLADITIDDVNNFLEQLFAGIYRIDNRMMIEGYIKTKEGSQKRFFAFNDVVITRPVISKMVKINASIDGERFNTYRGDGLIISTPTGSTAYNLAVGGPMVYPLTQAFILTPISAHSLTQRPLVVPADFTIELNSPDEKVIAVIDGQDDYEMHEGDILVIKGAAEGAKLLHRKERNYFSVLREKLKWGDEH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JQIX01000065
EMBL· GenBank· DDBJ
RRS29854.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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