A0A424Z2V5 · A0A424Z2V5_9BACT

  • Protein
    6,7-dimethyl-8-ribityllumazine synthase
  • Gene
    ribH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

Catalytic activity

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.

Features

Showing features for binding site, active site.

115420406080100120140
TypeIDPosition(s)Description
Binding site235-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site57-595-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site81-835-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site86-87(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)
Active site89Proton donor
Binding site1145-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site128(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentriboflavin synthase complex
Molecular Function6,7-dimethyl-8-ribityllumazine synthase activity
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6,7-dimethyl-8-ribityllumazine synthase
  • EC number
  • Short names
    DMRL synthase
    ; LS
    ; Lumazine synthase

Gene names

    • Name
      ribH
    • ORF names
      A2J15_007420
      , DZD40_00185
      , GC018_02215
      , GC019_01320

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • 54L
    • HV10
    • VIC_4/VIC
    • VIC_5/VIC
  • Taxonomic lineage
    Bacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Campylobacteraceae > Campylobacter

Accessions

  • Primary accession
    A0A424Z2V5

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the DMRL synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    154
  • Mass (Da)
    16,789
  • Last updated
    2019-05-08 v1
  • Checksum
    EA6A8EF45AAB3DE2
MNIIEGKLNLHSNANIAIINARFNHIITDRLVEGAKDAFLRHGGKEENLSLILVPGVFEIPFILKKAIESHQFDGICCVGAVIRGSTPHFDYISAETTKGVANVSLNHNTPVSFGILTTDTIEQAIERAGSKVGNKGFEAMITVIEMLNLSKEF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP031611
EMBL· GenBank· DDBJ
AXP09475.1
EMBL· GenBank· DDBJ
Genomic DNA
WHMG01000002
EMBL· GenBank· DDBJ
MPV95055.1
EMBL· GenBank· DDBJ
Genomic DNA
WHMF01000003
EMBL· GenBank· DDBJ
MPV98007.1
EMBL· GenBank· DDBJ
Genomic DNA
QURW01000001
EMBL· GenBank· DDBJ
RQD88655.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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