A0A411PKB2 · A0A411PKB2_9GAMM

  • Protein
    Bifunctional adenosylcobalamin biosynthesis protein
  • Gene
    cobU
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

Catalytic activity

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site7-14GTP (UniProtKB | ChEBI)
Binding site35-37GTP (UniProtKB | ChEBI)
Active site51GMP-histidine intermediate
Binding site71GTP (UniProtKB | ChEBI)
Binding site93GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionadenosylcobinamide kinase (ATP-specific) activity
Molecular Functionadenosylcobinamide kinase (GTP-specific) activity
Molecular FunctionATP binding
Molecular Functioncobinamide phosphate guanylyltransferase activity
Molecular FunctionGTP binding
Biological Processcobalamin biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional adenosylcobalamin biosynthesis protein
  • EC number

Gene names

    • Name
      cobU
    • ORF names
      EXU30_15175

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • D4-2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella

Accessions

  • Primary accession
    A0A411PKB2

Proteomes

Family & Domains

Sequence similarities

Belongs to the CobU/CobP family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    210
  • Mass (Da)
    23,302
  • Last updated
    2019-05-08 v1
  • Checksum
    D915262A770856F9
MIQLILGGARSGKSHFGESAVAKFANLGQSCVYLATAQAFDDEMHQRIERHQQDRAHVTHPELKIEWQLLEEPLYLAETLKLIDKPNQTIFVDCLTLYLTQHLLKQGDSSDEAVALRDAQPNAIVRAQLDKVNLSQNWQQQKQQLLAVLPKMKSNLVIVSNEVGSGIVPMGELSREFVDEAGWLNQAIAQIADQVTLVVAGLPLSLKGDK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP036200
EMBL· GenBank· DDBJ
QBF83870.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp