Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A411DR94 · A0A411DR94_CHRID

Function

function

Involved in the catabolism of quinolinic acid (QA).

Pathway

Cofactor biosynthesis; NAD+ biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.

Features

Showing features for binding site.

128620406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site103substrate
Binding site136-138substrate
Binding site160substrate
Binding site170substrate
Binding site203substrate
Binding site224substrate
Binding site247-249substrate
Binding site268-270substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionnicotinate-nucleotide diphosphorylase (carboxylating) activity
Biological ProcessNAD biosynthetic process
Biological Processquinolinate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    nicotinate-nucleotide diphosphorylase (carboxylating)
  • EC number
  • Alternative names
    • Quinolinate phosphoribosyltransferase [decarboxylating]

Gene names

    • Name
      nadC
    • ORF names
      EU348_17545

Organism names

Accessions

  • Primary accession
    A0A411DR94

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain, coiled coil.

Type
IDPosition(s)Description
Domain28-113Quinolinate phosphoribosyl transferase N-terminal
Domain115-283Quinolinate phosphoribosyl transferase C-terminal
Coiled coil193-220

Sequence similarities

Belongs to the NadC/ModD family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    286
  • Mass (Da)
    31,772
  • Last updated
    2019-05-08 v1
  • MD5 Checksum
    90B90C2B6B14245E2B6FDF8D6E5EA254
MKRPAYVTDKALKTFIKNALEEDIQDGDHSTLSTIPQDLVQSAKLLVKQDCILAGVELAEIIFKTFDKNLKVEVFIKDGTPCKFGDVALIVTGSARSILSTERFVLNCMQRMSGIATLTHEWDSRLVGTKTKLLDTRKTTPNFRMCEKWAVAIGGGTNHRYGLYDMIMLKDNHIDYNGSITNAVAMAKDYVKKNKKKLKIEVETRNLEEVQEAINAKVDRIMLDNMDVKTMKEAVKMINGSCESEASGGITRDMLKEIASTGVTYISVGALTHSAENIDLSLKAVK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP035532
EMBL· GenBank· DDBJ
QBA22882.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help