A0A410N6Z8 · A0A410N6Z8_9RHAB
- ProteinReplicase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2140 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- GTP + H2O = GDP + H+ + phosphate
- a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine
- a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H+ + S-adenosyl-L-homocysteine
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | host cell cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | hydrolase activity | |
Molecular Function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity | |
Molecular Function | RNA-dependent RNA polymerase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameReplicase
- EC number
- Alternative names
Organism names
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales > Rhabdoviridae > Betapaprhavirus > Betapaprhavirus frugiperda
Accessions
- Primary accessionA0A410N6Z8
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 566-740 | RdRp catalytic | ||||
Sequence: NKFMVSLDFSKWNTNMRAPDTQPFYHTIDTMFGLENCFTRTHEMFYNSFLYLIDGSYLPTIVDDGFKTDIGCWRHHLGGIEGLRQKGWTLWTVMLIRLVAEKYIFNMSIMGQGDNQMLLLTFDSNIPEEYALSQVNDFLQSLKDKLSLIGPPLKLEETWISKDFYLYGKYPIKGG | ||||||
Domain | 1650-1846 | Mononegavirus-type SAM-dependent 2'-O-MTase | ||||
Sequence: RPAPLPTSGAYKLSSVLPLLGSRALTKCLCLADGTGGFTRTLALRDDSKTIVFNTLVTDQDYVTQMDPIQNIPDIADLPISCQKKVVGLREVNDYPTDITSPDFGHQILDRFGGDFILVTGDAEDPSLHHSGNVLALFKAYMDISLIVNSVHGIFKIHTHRRSVLHQALVILLTYYDSVIVVRSQFSLRSNNEFYLV |
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,140
- Mass (Da)244,207
- Last updated2019-05-08 v1
- ChecksumA88C0DFA6728778E