A0A401RWM6 · A0A401RWM6_CHIPU
- ProteinRho-associated protein kinase 1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1286 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+This reaction proceeds in the forward direction.
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 105 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | bleb | |
Cellular Component | centriole | |
Cellular Component | cytoplasmic stress granule | |
Cellular Component | Golgi membrane | |
Cellular Component | lamellipodium | |
Cellular Component | plasma membrane | |
Cellular Component | ruffle | |
Molecular Function | ATP binding | |
Molecular Function | histone H2AS1 kinase activity | |
Molecular Function | metal ion binding | |
Molecular Function | Rho-dependent protein serine/threonine kinase activity | |
Molecular Function | small GTPase binding | |
Biological Process | actomyosin structure organization | |
Biological Process | cortical actin cytoskeleton organization | |
Biological Process | embryonic morphogenesis | |
Biological Process | mitotic cytokinesis | |
Biological Process | peptidyl-threonine phosphorylation | |
Biological Process | regulation of cell junction assembly | |
Biological Process | Rho protein signal transduction |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRho-associated protein kinase 1
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Elasmobranchii > Galeomorphii > Galeoidea > Orectolobiformes > Hemiscylliidae > Chiloscyllium
Accessions
- Primary accessionA0A401RWM6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, coiled coil, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 76-392 | Protein kinase | |||
Domain | 264-332 | AGC-kinase C-terminal | |||
Coiled coil | 350-604 | ||||
Domain | 405-481 | REM-1 | |||
Coiled coil | 652-1035 | ||||
Domain | 877-943 | RhoBD | |||
Domain | 1048-1247 | PH | |||
Domain | 1158-1213 | Phorbol-ester/DAG-type | |||
Compositional bias | 1253-1272 | Polar residues | |||
Region | 1253-1286 | Disordered | |||
Sequence similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,286
- Mass (Da)150,349
- Last updated2019-05-08 v1
- ChecksumB6C473F4C62212D1
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1253-1272 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BEZZ01000012 EMBL· GenBank· DDBJ | GCC22499.1 EMBL· GenBank· DDBJ | Genomic DNA |