A0A401PMS8 · A0A401PMS8_SCYTO

Function

function

Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • (9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
    This reaction proceeds in the forward direction.
  • (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA
    This reaction proceeds in the forward direction.
  • 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
    This reaction proceeds in the forward direction.
  • an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA
    EC:2.3.1.15 (UniProtKB | ENZYME | Rhea)
  • dodecanoyl-CoA + sn-glycerol 3-phosphate = 1-dodecanoyl-sn-glycerol 3-phosphate + CoA
    This reaction proceeds in the forward direction.
  • hexadecanoyl-CoA + sn-glycerol 3-phosphate = 1-hexadecanoyl-sn-glycero-3-phosphate + CoA
    This reaction proceeds in the forward direction.
  • octadecanoyl-CoA + sn-glycerol 3-phosphate = 1-octadecanoyl-sn-glycero-3-phosphate + CoA
    This reaction proceeds in the forward direction.

Pathway

Lipid metabolism.
Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.

GO annotations

AspectTerm
Cellular Componentmitochondrial outer membrane
Cellular Componentplasma membrane
Molecular Functionglycerol-3-phosphate O-acyltransferase activity
Molecular Functionsn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity
Biological ProcessCDP-diacylglycerol biosynthetic process
Biological Processfatty acid metabolic process
Biological Processglycerol-3-phosphate metabolic process
Biological Processtriglyceride biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-3-phosphate acyltransferase 1, mitochondrial
  • EC number

Gene names

    • ORF names
      scyTo_0003527

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Elasmobranchii > Galeomorphii > Galeoidea > Carcharhiniformes > Scyliorhinidae > Scyliorhinus

Accessions

  • Primary accession
    A0A401PMS8

Proteomes

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion outer membrane
; Multi-pass membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain240-373Phospholipid/glycerol acyltransferase
Region680-709Disordered

Sequence similarities

Belongs to the GPAT/DAPAT family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    836
  • Mass (Da)
    94,623
  • Last updated
    2019-05-08 v1
  • Checksum
    2197714060815017
MWVKAAGVFEWVSDMAESVLISSVMDAACLPNTRAQSGNRMKNSNDEQVEYSPSSAVFRSAAATGKESLLSRKRPFVGRCCHVCSPISRDKLFNASIPSQGLRNVIYINETHTRYRGWLARRLCYVLFVQERDVHRDMFPRNVIENVLNNNRVQVAIMETVAERMPAETLAQPDSKAVGKVKRKARGILQQMVANISPVVIRLTGWVLLKLFNGFFWSIQIHKGQLEMVKKAAAEQNVPLIFLPVHKSHIDYLLLTFILFCHNIKAPHIAAGNNLNIPIFSTLIRKLGGFFIRRKLDICADGRKDILYRAVLRVYIAELLRQQQFMEIFVEGTRSRSGKPYMAMTGLLSIVVDSLYENTVADVMIIPVGISYDRIIEGNYNSEQLGKPKKKESLWGVAQGVFRMLRKNFGCVRVDFGQPFSVKEYIDAQRNRPLPAALSLEEILLPSIITDRPGLDYAEPDQVPIINSRDFSDEQYRRQLISNVAKHALFTASRCSAVMSTHIVACLLLYRHRKGVHLSKLVEDFFSMKEVVLARDFDLGFSGNSEDVVMHALHLLGDCVNVRSSRRNSEFFIAPTTTIPALFELNFYSNGIFQVFLTEAILACSLCAILKEKITEPSQMELTVSQERLIRTAASLCHLLSNEVAVALPCQAVYQVCHDAVGKFIQYGILMVAEEDLSPSPTEETWANKYPDGLSWRSDEEDDSDYGEEQRDRYLKVSQSQDHQEFITFLQRLLGPLLEAYFAAAVFIQSFRVPVEEMEYISKFHKYLLSRTEMKIAVFGESATFCLAKSAVKTLKDLGVFKAQKSGSSTLELSNTFLPLINRQKLLEYILNFTIA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BFAA01000968
EMBL· GenBank· DDBJ
GCB74437.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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