A0A401PEU5 · A0A401PEU5_SCYTO
- Proteinreceptor protein-tyrosine kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids988 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Features
Showing features for binding site, active site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | dendrite | |
Cellular Component | early endosome | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | transmembrane-ephrin receptor activity | |
Biological Process | axon guidance |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namereceptor protein-tyrosine kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Elasmobranchii > Galeomorphii > Galeoidea > Carcharhiniformes > Scyliorhinidae > Scyliorhinus
Accessions
- Primary accessionA0A401PEU5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 547-569 | Helical | ||||
Sequence: VLLVSVAGSAVLVVILISAFVIS |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-19 | |||||
Sequence: MAGIVQLTAWALVLGTAAA | ||||||
Chain | PRO_5019091739 | 20-988 | receptor protein-tyrosine kinase | |||
Sequence: FYNSKVLPPNQVILLDSRSVQGELGWEAFPAEGGWEEVSIMDEKNTPIRTYQVCNVMEANQNNWLRTDWIPREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLFYFESNNDNEWYISENRYIKIDTIAADESFTQVDIGDRVMKLNTEVRDVGPLTKKGFYLAFQDVGACIALVSVRVFYKKCPLTVHNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDEPKMYCGADGEWLVPIGNCLCNTGYEEQNGECQACKIGYYKALSTDSSCSKCPPHSSSTQEALTYCICERGYFRAENDPLSMPCTRPPSAPLNLISNINETSVILEWSPPQNNGGRHDVTYNVICKKCTNDLSRCNPCGSGIHFVPQQTGLKNTKVSITDLQAHTNYTFEVFAVNGVTNLNPNHDRSVLVTVTTNQAAPSSVGLIQAKEVTRHGVSLVWPEPERPNGVILEYEIKYYEKDQNERSYRIVKTLSRSTEIKGLNPLTAYMFHVRARTAAGYGDFSAPFQFITNSAPSAIIGDGASPTVLLVSVAGSAVLVVILISAFVISRRRRKYSKAKQEADEEKHVHNGQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIERVIGVGEFGEVCSGRLKMPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGQFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKERNDRPKFAQIVNMLDKLIRNPSSLKRTAVSESTRPSTALLDPGTPDFSALGSVGDWLQVIKMDRYKDNFTAAGYTSLEAVVHMNQDDLARIGITTMVHQSKILSSVQGMRAQMQQMQGRMVPV | ||||||
Disulfide bond | 73↔191 | |||||
Sequence: CNVMEANQNNWLRTDWIPREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLFYFESNNDNEWYISENRYIKIDTIAADESFTQVDIGDRVMKLNTEVRDVGPLTKKGFYLAFQDVGAC | ||||||
Disulfide bond | 108↔118 | |||||
Sequence: CNSLPGVMGTC |
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 30-209 | Eph LBD | ||||
Sequence: QVILLDSRSVQGELGWEAFPAEGGWEEVSIMDEKNTPIRTYQVCNVMEANQNNWLRTDWIPREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLFYFESNNDNEWYISENRYIKIDTIAADESFTQVDIGDRVMKLNTEVRDVGPLTKKGFYLAFQDVGACIALVSVRVFYKKCPLTVH | ||||||
Domain | 328-438 | Fibronectin type-III | ||||
Sequence: PPSAPLNLISNINETSVILEWSPPQNNGGRHDVTYNVICKKCTNDLSRCNPCGSGIHFVPQQTGLKNTKVSITDLQAHTNYTFEVFAVNGVTNLNPNHDRSVLVTVTTNQA | ||||||
Domain | 439-534 | Fibronectin type-III | ||||
Sequence: APSSVGLIQAKEVTRHGVSLVWPEPERPNGVILEYEIKYYEKDQNERSYRIVKTLSRSTEIKGLNPLTAYMFHVRARTAAGYGDFSAPFQFITNSA | ||||||
Domain | 622-883 | Protein kinase | ||||
Sequence: IKIERVIGVGEFGEVCSGRLKMPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGQFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKERNDRPKFAQIVNMLDKLI | ||||||
Domain | 913-977 | SAM | ||||
Sequence: SALGSVGDWLQVIKMDRYKDNFTAAGYTSLEAVVHMNQDDLARIGITTMVHQSKILSSVQGMRAQ |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length988
- Mass (Da)110,266
- Last updated2019-05-08 v1
- Checksum927E3AE2FD89E197
Keywords
- Technical term