A0A401P7R7 · A0A401P7R7_SCYTO

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H+
    This reaction proceeds in the forward direction.
  • 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + di-(9Z)-octadecenoylglycerol + H+
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H+
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H+
    This reaction proceeds in the forward direction.
  • 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = H+ + hexadecanoate + hexadecanoyl-sn-glycero-3-phosphocholine
    This reaction proceeds in the forward direction.
  • 1,3-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycerol + H+
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O = (9Z)-octadecenoate + H+ + sn-glycero-3-phospho-L-serine
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = H+ + hexadecanoate + sn-glycerol 3-phosphocholine
    This reaction proceeds in the forward direction.
  • a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H+
    EC:3.1.1.32 (UniProtKB | ENZYME | Rhea)
  • a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H+ + sn-glycerol 3-phosphocholine
    EC:3.1.1.5 (UniProtKB | ENZYME | Rhea)
  • a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H+
    EC:3.1.1.3 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site162Nucleophile
Active site188Charge relay system
Binding site202Ca2+ (UniProtKB | ChEBI)
Binding site207Ca2+ (UniProtKB | ChEBI)
Active site273Charge relay system

GO annotations

AspectTerm
Cellular Componenthigh-density lipoprotein particle
Molecular Function1-acyl-2-lysophosphatidylserine acylhydrolase activity
Molecular Functionapolipoprotein binding
Molecular Functionheparin binding
Molecular Functionlipoprotein lipase activity
Molecular Functionlysophospholipase activity
Molecular Functionmetal ion binding
Molecular Functionphosphatidylserine 1-acylhydrolase activity
Molecular Functionphospholipase A1 activity
Biological Processfatty acid biosynthetic process
Biological Processtriglyceride catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Hepatic triacylglycerol lipase
  • EC number
  • Alternative names
    • Lipase member C
    • Lysophospholipase
    • Phospholipase A1

Gene names

    • ORF names
      scyTo_0001006

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Elasmobranchii > Galeomorphii > Galeoidea > Carcharhiniformes > Scyliorhinidae > Scyliorhinus

Accessions

  • Primary accession
    A0A401P7R7

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-21
ChainPRO_501927784122-495Hepatic triacylglycerol lipase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain346-481PLAT

Sequence similarities

Belongs to the AB hydrolase superfamily. Lipase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    495
  • Mass (Da)
    56,577
  • Last updated
    2019-05-08 v1
  • Checksum
    9847B8DB112D3AC5
MNNWAQISLLLFICAILKAQSARTTRKDDTSVGRRKAQAESIKYCLFKGPSPNKEICCFTPNKAVTLETCGFNTSHPLVAIVHGWTLDGMYESWIWKMAAALKVRRKNINVLVIDWLTLAHQHYPIAVKNTRIVGQEIANLLDWLEEFFGFPKGKVHLIGYSLGAHVSGFAGNYITGTNRIGRITGLDPAGPLFEGMSSTERLSPDDANFVDAVHTFTQEHIGLSVGINQPVAHYDFYPNGGTIQPGCHLKHMYSHIAQYGILGITETVKCAHERSVHLFIDSLLNEDKQIVGYWCNDLSTFNKGTCLSCRKNRCNTLGYNIKKVRTQRSKKMYFKTRANMPYKVYHYQFKIRFINHMEHNILEPSLTVSLFGTEGDAENLPIKLVESITTNKTYSFLIHTDVNIGDLMLLKFKWENPVAWTNLWKTVQTYFQWGQNHLNPELIVRKIRIKAGETQHKVTFCPSNIDMHLQPAQEKKFVRCVSDRSRKRHRRISI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BFAA01000208
EMBL· GenBank· DDBJ
GCB69153.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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