A0A3V2G0Q4 · A0A3V2G0Q4_SALET

Function

function

Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyruvate (UniProtKB | Rhea| CHEBI:15361 )

Note: Binds 1 pyruvoyl group covalently per subunit.

Pathway

Cofactor biosynthesis; (R)-pantothenate biosynthesis; beta-alanine from L-aspartate: step 1/1.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site25Schiff-base intermediate with substrate; via pyruvic acid
Binding site57substrate
Active site58Proton donor
Binding site73-75substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionaspartate 1-decarboxylase activity
Biological Processalanine biosynthetic process
Biological Processpantothenate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      panD
    • ORF names
      A4W49_16015
      , A4W57_09700
      , AIK92_13015
      , ASH82_22675
      , CB395_22660
      , CIL65_22840
      , D6J51_10130
      , D6K67_11070
      , DKU10_07530
      , DOJ23_22640
      , DP829_11585
      , DPJ44_10765
      , DPS10_20950
      , DQQ63_23220
      , DY868_16200
      , EUX26_12840
      , F9G64_22840
      , G0D76_16610
      , G3408_003568
      , G4B28_004447
      , G4B35_004313
      , G4I58_003768
      , G4I61_004217
      , G4L02_003536
      , G4Y23_003715
      , G9C15_001326
      , GCZ77_18385

Organism names

Accessions

  • Primary accession
    A0A3V2G0Q4
  • Secondary accessions
    • A0A6C8XJ93

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_50359718181-24Aspartate 1-decarboxylase beta chain
Modified residue25Pyruvic acid (Ser)
ChainPRO_503597181925-126Aspartate 1-decarboxylase alpha chain

Post-translational modification

Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

Keywords

Interaction

Subunit

Heterooctamer of four alpha and four beta subunits.

Family & Domains

Sequence similarities

Belongs to the PanD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    126
  • Mass (Da)
    13,887
  • Last updated
    2019-05-08 v1
  • MD5 Checksum
    F143CAD564DD47211293B3B2D157B134
MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWRPKVAYFEGDNEMKRTAKAIPVQVA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAHCWL010000005
EMBL· GenBank· DDBJ
EBU6914563.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHFAS010000073
EMBL· GenBank· DDBJ
EBV3764301.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHGTQ010000047
EMBL· GenBank· DDBJ
EBV9203380.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHIGD010000005
EMBL· GenBank· DDBJ
EBW4104593.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHIXO010000006
EMBL· GenBank· DDBJ
EBW6732466.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHKXZ010000024
EMBL· GenBank· DDBJ
EBX3357288.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHOXC010000006
EMBL· GenBank· DDBJ
EBY7384885.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHPAD010000006
EMBL· GenBank· DDBJ
EBY7626971.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHWIJ010000007
EMBL· GenBank· DDBJ
ECB0524043.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKLND010000047
EMBL· GenBank· DDBJ
ECT0412891.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKPQX010000008
EMBL· GenBank· DDBJ
ECU3484204.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKTKA010000063
EMBL· GenBank· DDBJ
ECV4808638.1
EMBL· GenBank· DDBJ
Genomic DNA
AALIQJ010000057
EMBL· GenBank· DDBJ
EDA0177670.1
EMBL· GenBank· DDBJ
Genomic DNA
AALLSV010000013
EMBL· GenBank· DDBJ
EDA9403014.1
EMBL· GenBank· DDBJ
Genomic DNA
AALLTD010000007
EMBL· GenBank· DDBJ
EDA9437081.1
EMBL· GenBank· DDBJ
Genomic DNA
AAMGJL010000008
EMBL· GenBank· DDBJ
EDH0980132.1
EMBL· GenBank· DDBJ
Genomic DNA
AAMIHV010000043
EMBL· GenBank· DDBJ
EDH6431598.1
EMBL· GenBank· DDBJ
Genomic DNA
DAAMJL010000006
EMBL· GenBank· DDBJ
HAC6916783.1
EMBL· GenBank· DDBJ
Genomic DNA
DAARLP010000007
EMBL· GenBank· DDBJ
HAE2914405.1
EMBL· GenBank· DDBJ
Genomic DNA
DAARUC010000053
EMBL· GenBank· DDBJ
HAE3942377.1
EMBL· GenBank· DDBJ
Genomic DNA
DAARUZ010000044
EMBL· GenBank· DDBJ
HAE4051119.1
EMBL· GenBank· DDBJ
Genomic DNA
DAASLG010000011
EMBL· GenBank· DDBJ
HAE6002113.1
EMBL· GenBank· DDBJ
Genomic DNA
DAASLQ010000088
EMBL· GenBank· DDBJ
HAE6034003.1
EMBL· GenBank· DDBJ
Genomic DNA
DAASRW010000008
EMBL· GenBank· DDBJ
HAE6747771.1
EMBL· GenBank· DDBJ
Genomic DNA
DAATPN010000010
EMBL· GenBank· DDBJ
HAE9562920.1
EMBL· GenBank· DDBJ
Genomic DNA
DAAUAM010000011
EMBL· GenBank· DDBJ
HAF0862166.1
EMBL· GenBank· DDBJ
Genomic DNA
RSGD01000008
EMBL· GenBank· DDBJ
MID45863.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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