A0A3V2FXT2 · A0A3V2FXT2_SALET
- ProteinProbable cytosol aminopeptidase
- GenepepA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids503 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
Catalytic activity
- Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.
Cofactor
Note: Binds 2 manganese ions per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 270 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 275 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 275 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Active site | 282 | ||||
Binding site | 293 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 352 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 354 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 354 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Active site | 356 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | manganese ion binding | |
Molecular Function | metalloaminopeptidase activity | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable cytosol aminopeptidase
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A3V2FXT2
- Secondary accessions
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length503
- Mass (Da)54,890
- Last updated2019-05-08 v1
- MD5 Checksum340BDF3D5D1AF371A7F206B8AB170C41
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAHCWL010000008 EMBL· GenBank· DDBJ | EBU6915163.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHFAS010000032 EMBL· GenBank· DDBJ | EBV3762824.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHGTQ010000014 EMBL· GenBank· DDBJ | EBV9201679.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIGD010000008 EMBL· GenBank· DDBJ | EBW4105180.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIXO010000008 EMBL· GenBank· DDBJ | EBW6732866.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHKXZ010000009 EMBL· GenBank· DDBJ | EBX3355757.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHOXC010000008 EMBL· GenBank· DDBJ | EBY7385301.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHPAD010000008 EMBL· GenBank· DDBJ | EBY7627388.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHWIJ010000004 EMBL· GenBank· DDBJ | ECB0523217.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKLND010000006 EMBL· GenBank· DDBJ | ECT0409958.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKPQX010000004 EMBL· GenBank· DDBJ | ECU3483375.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKTKA010000026 EMBL· GenBank· DDBJ | ECV4807227.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALIQJ010000003 EMBL· GenBank· DDBJ | EDA0173871.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLSV010000007 EMBL· GenBank· DDBJ | EDA9402067.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLTD010000010 EMBL· GenBank· DDBJ | EDA9437683.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMGJL010000002 EMBL· GenBank· DDBJ | EDH0978129.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMIHV010000006 EMBL· GenBank· DDBJ | EDH6428720.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAMJL010000002 EMBL· GenBank· DDBJ | HAC6915252.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARLP010000003 EMBL· GenBank· DDBJ | HAE2913181.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUC010000045 EMBL· GenBank· DDBJ | HAE3942222.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUZ010000006 EMBL· GenBank· DDBJ | HAE4048221.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLG010000004 EMBL· GenBank· DDBJ | HAE6000611.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLQ010000089 EMBL· GenBank· DDBJ | HAE6034007.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASRW010000004 EMBL· GenBank· DDBJ | HAE6746452.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAATPN010000002 EMBL· GenBank· DDBJ | HAE9560597.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAUAM010000068 EMBL· GenBank· DDBJ | HAF0864958.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RSGD01000002 EMBL· GenBank· DDBJ | MID44072.1 EMBL· GenBank· DDBJ | Genomic DNA |