A0A3T3GB91 · A0A3T3GB91_SALET
- ProteinPhosphoenolpyruvate-protein phosphotransferase
- GeneptsI
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids575 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
Catalytic activity
- L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 189 | Tele-phosphohistidine intermediate | |||
Binding site | 296 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 332 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 431 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 454-455 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 455 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 465 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Active site | 502 | Proton donor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | kinase activity | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoenolpyruvate-protein phosphotransferase activity | |
Biological Process | phosphoenolpyruvate-dependent sugar phosphotransferase system | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoenolpyruvate-protein phosphotransferase
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A3T3GB91
- Secondary accessions
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 4-126 | Phosphotransferase system enzyme I N-terminal | |||
Domain | 152-223 | PEP-utilising enzyme mobile | |||
Domain | 250-541 | PEP-utilising enzyme C-terminal | |||
Sequence similarities
Belongs to the PEP-utilizing enzyme family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length575
- Mass (Da)63,399
- Last updated2019-05-08 v1
- MD5 ChecksumB96BC0FF4697B548B32FB3535D90005B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAHCWL010000018 EMBL· GenBank· DDBJ | EBU6916558.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHFAS010000033 EMBL· GenBank· DDBJ | EBV3762874.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHGTQ010000021 EMBL· GenBank· DDBJ | EBV9202224.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHKXZ010000016 EMBL· GenBank· DDBJ | EBX3356708.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHPAD010000018 EMBL· GenBank· DDBJ | EBY7628810.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKLND010000002 EMBL· GenBank· DDBJ | ECT0408977.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKPQX010000003 EMBL· GenBank· DDBJ | ECU3483019.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLSV010000019 EMBL· GenBank· DDBJ | EDA9403731.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMGJL010000004 EMBL· GenBank· DDBJ | EDH0978959.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAMJL010000011 EMBL· GenBank· DDBJ | HAC6917793.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARLP010000006 EMBL· GenBank· DDBJ | HAE2914162.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUC010000002 EMBL· GenBank· DDBJ | HAE3938582.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUZ010000002 EMBL· GenBank· DDBJ | HAE4047413.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLG010000005 EMBL· GenBank· DDBJ | HAE6000935.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASRW010000005 EMBL· GenBank· DDBJ | HAE6746919.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAATPN010000003 EMBL· GenBank· DDBJ | HAE9561064.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAUAM010000001 EMBL· GenBank· DDBJ | HAF0860965.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RSGD01000006 EMBL· GenBank· DDBJ | MID45487.1 EMBL· GenBank· DDBJ | Genomic DNA |