A0A3T3GB00 · A0A3T3GB00_SALET
- ProteinCatalase-peroxidase
- GenekatG
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids726 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
Catalytic activity
- 2 H2O2 = O2 + 2 H2O
Cofactor
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
Features
Showing features for site, active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 102 | Transition state stabilizer | |||
Active site | 106 | Proton acceptor | |||
Binding site | 267 | Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | catalase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | cellular response to hydrogen peroxide | |
Biological Process | hydrogen peroxide catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCatalase-peroxidase
- EC number
- Short namesCP
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A3T3GB00
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for cross-link.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Cross-link | 105↔226 | Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with Met-252) | |||
Cross-link | 226↔252 | Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-105) | |||
Post-translational modification
Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
Interaction
Subunit
Homodimer or homotetramer.
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-16 | Polar residues | |||
Region | 1-33 | Disordered | |||
Domain | 139-424 | Plant heme peroxidase family profile | |||
Sequence similarities
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length726
- Mass (Da)79,656
- Last updated2019-05-08 v1
- Checksum7C4BA44439E9FFAB
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-16 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAHCWL010000009 EMBL· GenBank· DDBJ | EBU6915444.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHFAS010000013 EMBL· GenBank· DDBJ | EBV3761516.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHGTQ010000006 EMBL· GenBank· DDBJ | EBV9200547.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIGD010000009 EMBL· GenBank· DDBJ | EBW4105466.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIXO010000012 EMBL· GenBank· DDBJ | EBW6733602.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHKXZ010000007 EMBL· GenBank· DDBJ | EBX3355507.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHOXC010000012 EMBL· GenBank· DDBJ | EBY7386024.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHPAD010000009 EMBL· GenBank· DDBJ | EBY7627669.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHWIJ010000012 EMBL· GenBank· DDBJ | ECB0525011.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKLND010000020 EMBL· GenBank· DDBJ | ECT0411527.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKPQX010000010 EMBL· GenBank· DDBJ | ECU3484604.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALIQJ010000007 EMBL· GenBank· DDBJ | EDA0174555.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLSV010000014 EMBL· GenBank· DDBJ | EDA9403245.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLTD010000013 EMBL· GenBank· DDBJ | EDA9438227.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMGJL010000012 EMBL· GenBank· DDBJ | EDH0980684.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMIHV010000013 EMBL· GenBank· DDBJ | EDH6429806.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAMJL010000010 EMBL· GenBank· DDBJ | HAC6917684.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARLP010000009 EMBL· GenBank· DDBJ | HAE2914880.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUC010000019 EMBL· GenBank· DDBJ | HAE3940876.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUZ010000010 EMBL· GenBank· DDBJ | HAE4048868.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLG010000010 EMBL· GenBank· DDBJ | HAE6002075.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLQ010000046 EMBL· GenBank· DDBJ | HAE6032873.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASRW010000011 EMBL· GenBank· DDBJ | HAE6748354.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAATPN010000013 EMBL· GenBank· DDBJ | HAE9563348.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAUAM010000008 EMBL· GenBank· DDBJ | HAF0861915.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RSGD01000011 EMBL· GenBank· DDBJ | MID46438.1 EMBL· GenBank· DDBJ | Genomic DNA |