A0A3T3G9S8 · A0A3T3G9S8_SALET

Function

function

Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
    EC:2.7.13.3 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionphosphorelay sensor kinase activity
Biological Processprotein autophosphorylation
Biological Processregulation of DNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Sensor histidine kinase RcsC
  • EC number

Gene names

    • Name
      rcsC
    • ORF names
      A4W49_13520
      , A4W57_11355
      , AIK92_22465
      , ASH82_15645
      , CB395_22115
      , D6J51_14650
      , D6K67_15620
      , DKU10_13025
      , DOJ23_11400
      , DP829_10035
      , DPJ44_13360
      , DPS10_14370
      , DQQ63_03905
      , DY868_10840
      , EUX26_17200
      , F9G64_13120
      , G0D76_20410
      , G3408_003483
      , G4B28_000669
      , G4B35_004354
      , G4I58_002707
      , G4I61_001621
      , G4L02_002818
      , G4Y23_001946
      , G9C15_002019
      , GCZ77_13080

Organism names

Accessions

  • Primary accession
    A0A3T3G9S8
  • Secondary accessions
    • A0A6C8XQV7

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane16-38Helical
Transmembrane314-334Helical

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue479Phosphohistidine; by autocatalysis
Modified residue8754-aspartylphosphate

Post-translational modification

Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.

Keywords

Interaction

Subunit

Interacts with RcsD.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain476-692Histidine kinase
Domain705-805ABL
Domain826-940Response regulatory

Sequence similarities

Belongs to the RcsC family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    948
  • Mass (Da)
    106,336
  • Last updated
    2019-05-08 v1
  • MD5 Checksum
    2DE9D83D855C9EE49FC83AB8688B9754
MKYLASFRTTLKVSRYLFRALALLIWLLIAFVSVFYIVNALHQRESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLTAENGVMSSRARDDKMVVPDFEPLFADSDCAAMGSAWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGLREMPVERDDALKALHERIMKYRNAPQEESGNNLFWISQGARQGVGYFYALTPVYLANRLQALLGVEQPIRMENFFTPGSLPMGVTIIDENGHSLISLTGPDGNIKAEPRWMQERSWFGYTPGFRELVLKKSLPPSSLSIVYSVPVDLVLERIRILILNAILLNVLVGAGLFTLARMYERRIFIPAESDAQRLEEHEQFNRKIVASAPVGICILRTIDGVNILSNELAHTYLNMLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSTRVKMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLVTAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLGLYCFIEPDVPVSLNGDPMRLQQVISNLLSNAIKFTDIGYIVLHVRCDGDYLSIRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGSQFTLRIPLYGAQYPVKKSVEGLAGTCCWLAVRNTSLCQFIETSLARSGVHTQRYEGQEPAADDILIVDDALEHTWQGRAAVVFCRRHIGIPLERAPGEWVHSVASVHELPALLARIYSIELDSEALSSALPTTDKTADSNDDMMILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNAIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVVGVTANALAEEKQRCLESGMDSCLSKPVTLDVLKQTLAVYAERVRKTRA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAHCWL010000010
EMBL· GenBank· DDBJ
EBU6915618.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHFAS010000021
EMBL· GenBank· DDBJ
EBV3762143.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHGTQ010000018
EMBL· GenBank· DDBJ
EBV9202026.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHIGD010000007
EMBL· GenBank· DDBJ
EBW4105097.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHIXO010000004
EMBL· GenBank· DDBJ
EBW6732161.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHKXZ010000010
EMBL· GenBank· DDBJ
EBX3356030.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHOXC010000010
EMBL· GenBank· DDBJ
EBY7385747.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHPAD010000010
EMBL· GenBank· DDBJ
EBY7627844.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHWIJ010000011
EMBL· GenBank· DDBJ
ECB0524878.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKLND010000002
EMBL· GenBank· DDBJ
ECT0409209.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKPQX010000003
EMBL· GenBank· DDBJ
ECU3483183.1
EMBL· GenBank· DDBJ
Genomic DNA
AALIQJ010000019
EMBL· GenBank· DDBJ
EDA0175789.1
EMBL· GenBank· DDBJ
Genomic DNA
AALLSV010000009
EMBL· GenBank· DDBJ
EDA9402526.1
EMBL· GenBank· DDBJ
Genomic DNA
AALLTD010000008
EMBL· GenBank· DDBJ
EDA9437403.1
EMBL· GenBank· DDBJ
Genomic DNA
AAMGJL010000004
EMBL· GenBank· DDBJ
EDH0979116.1
EMBL· GenBank· DDBJ
Genomic DNA
AAMIHV010000039
EMBL· GenBank· DDBJ
EDH6431491.1
EMBL· GenBank· DDBJ
Genomic DNA
DAAMJL010000009
EMBL· GenBank· DDBJ
HAC6917507.1
EMBL· GenBank· DDBJ
Genomic DNA
DAARLP010000006
EMBL· GenBank· DDBJ
HAE2914320.1
EMBL· GenBank· DDBJ
Genomic DNA
DAARUC010000002
EMBL· GenBank· DDBJ
HAE3938740.1
EMBL· GenBank· DDBJ
Genomic DNA
DAARUZ010000046
EMBL· GenBank· DDBJ
HAE4051160.1
EMBL· GenBank· DDBJ
Genomic DNA
DAASLG010000005
EMBL· GenBank· DDBJ
HAE6001093.1
EMBL· GenBank· DDBJ
Genomic DNA
DAASLQ010000018
EMBL· GenBank· DDBJ
HAE6031499.1
EMBL· GenBank· DDBJ
Genomic DNA
DAASRW010000005
EMBL· GenBank· DDBJ
HAE6747077.1
EMBL· GenBank· DDBJ
Genomic DNA
DAATPN010000003
EMBL· GenBank· DDBJ
HAE9561222.1
EMBL· GenBank· DDBJ
Genomic DNA
DAAUAM010000018
EMBL· GenBank· DDBJ
HAF0862840.1
EMBL· GenBank· DDBJ
Genomic DNA
RSGD01000028
EMBL· GenBank· DDBJ
MID47656.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help