A0A3T3G9S8 · A0A3T3G9S8_SALET
- ProteinSensor histidine kinase RcsC
- GenercsC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids948 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
Catalytic activity
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | phosphorelay sensor kinase activity | |
Biological Process | protein autophosphorylation | |
Biological Process | regulation of DNA-templated transcription |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSensor histidine kinase RcsC
- EC number
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A3T3G9S8
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 16-38 | Helical | |||
Transmembrane | 314-334 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 479 | Phosphohistidine; by autocatalysis | |||
Modified residue | 875 | 4-aspartylphosphate | |||
Post-translational modification
Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
Keywords
- PTM
Interaction
Subunit
Interacts with RcsD.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length948
- Mass (Da)106,336
- Last updated2019-05-08 v1
- MD5 Checksum2DE9D83D855C9EE49FC83AB8688B9754
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAHCWL010000010 EMBL· GenBank· DDBJ | EBU6915618.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHFAS010000021 EMBL· GenBank· DDBJ | EBV3762143.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHGTQ010000018 EMBL· GenBank· DDBJ | EBV9202026.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIGD010000007 EMBL· GenBank· DDBJ | EBW4105097.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIXO010000004 EMBL· GenBank· DDBJ | EBW6732161.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHKXZ010000010 EMBL· GenBank· DDBJ | EBX3356030.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHOXC010000010 EMBL· GenBank· DDBJ | EBY7385747.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHPAD010000010 EMBL· GenBank· DDBJ | EBY7627844.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHWIJ010000011 EMBL· GenBank· DDBJ | ECB0524878.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKLND010000002 EMBL· GenBank· DDBJ | ECT0409209.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKPQX010000003 EMBL· GenBank· DDBJ | ECU3483183.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALIQJ010000019 EMBL· GenBank· DDBJ | EDA0175789.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLSV010000009 EMBL· GenBank· DDBJ | EDA9402526.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLTD010000008 EMBL· GenBank· DDBJ | EDA9437403.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMGJL010000004 EMBL· GenBank· DDBJ | EDH0979116.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMIHV010000039 EMBL· GenBank· DDBJ | EDH6431491.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAMJL010000009 EMBL· GenBank· DDBJ | HAC6917507.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARLP010000006 EMBL· GenBank· DDBJ | HAE2914320.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUC010000002 EMBL· GenBank· DDBJ | HAE3938740.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUZ010000046 EMBL· GenBank· DDBJ | HAE4051160.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLG010000005 EMBL· GenBank· DDBJ | HAE6001093.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLQ010000018 EMBL· GenBank· DDBJ | HAE6031499.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASRW010000005 EMBL· GenBank· DDBJ | HAE6747077.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAATPN010000003 EMBL· GenBank· DDBJ | HAE9561222.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAUAM010000018 EMBL· GenBank· DDBJ | HAF0862840.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RSGD01000028 EMBL· GenBank· DDBJ | MID47656.1 EMBL· GenBank· DDBJ | Genomic DNA |