A0A3T3G9L7 · A0A3T3G9L7_SALET

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 1 [2Fe-2S] cluster per subunit.
[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentoxidoreductase complex
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular Functionmolybdopterin cofactor binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionquinone binding
Biological ProcessATP synthesis coupled electron transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase
  • EC number

Gene names

    • Name
      nuoG
    • ORF names
      AIK92_11640
      , CIL65_06330
      , D6J51_14375
      , D6K67_15345
      , DKU10_12750
      , DOJ23_05600
      , DP829_09760
      , DPJ44_13085
      , DPS10_14095
      , DQQ63_03630
      , DY868_10565
      , G0D76_20135

Organism names

Accessions

  • Primary accession
    A0A3T3G9L7
  • Secondary accessions
    • A0A6C8XJY4

Proteomes

Subcellular Location

PTM/Processing

Keywords

Interaction

Subunit

Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-852Fe-2S ferredoxin-type
Domain85-1244Fe-4S His(Cys)3-ligated-type
Domain223-2794Fe-4S Mo/W bis-MGD-type

Sequence similarities

Belongs to the complex I 75 kDa subunit family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    910
  • Mass (Da)
    100,272
  • Last updated
    2019-05-08 v1
  • MD5 Checksum
    1287EA0E814D2FDDEF73D095443BF73B
MLMATIHVDGKEYEVNGADNLLQACLSLGLDIPYFCWHPALGSVGACRQCAVKQYQNAEDTRGRLVMSCMTPATDGTFISIDDEEAKQFRESVVEWLMTNHPHDCPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRYYKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRKWDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLKDRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASIESNFALRELVGAENFYTGIARGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALAVRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAPVEDQARLGFAIAHALDNTAPAVDGIDSDLQNKIDVIVQALAGAKKPLIISGTNAGSSEVIQAAANVAKALKGRGADVGITMIARSVNSMGLGMMGGGSLDDALGELETGSADAVVVLENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNEGRAQRFFQVYDPAYYDNKTIMLESWRWLHSLHSTVENREVDWTQLDHVIDAVIAAMPQFAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDKDTMFAFSMEGNNQPTAPRSEIPFAWAPGWNSPQAWNKFQDEVGGKLRHGDPGVRLIEATEGGLDYFTTVPASFQAQDGQWRIAPYYHLFGSDELSQRSPVFQSRMPQPYIKLNPADAAKLGVNAGTRVSFSYDGNTVTLPVEISEGLAAGQVGLPMGMPGIAPVLAGARLEDLREAQQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAHCWL010000010
EMBL· GenBank· DDBJ
EBU6915564.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHFAS010000009
EMBL· GenBank· DDBJ
EBV3761018.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHIGD010000007
EMBL· GenBank· DDBJ
EBW4105042.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHIXO010000004
EMBL· GenBank· DDBJ
EBW6732106.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHKXZ010000010
EMBL· GenBank· DDBJ
EBX3355975.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHOXC010000010
EMBL· GenBank· DDBJ
EBY7385692.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHPAD010000010
EMBL· GenBank· DDBJ
EBY7627789.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKLND010000002
EMBL· GenBank· DDBJ
ECT0409154.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKPQX010000003
EMBL· GenBank· DDBJ
ECU3483128.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKTKA010000009
EMBL· GenBank· DDBJ
ECV4805508.1
EMBL· GenBank· DDBJ
Genomic DNA
DAAMJL010000009
EMBL· GenBank· DDBJ
HAC6917452.1
EMBL· GenBank· DDBJ
Genomic DNA
RSGD01000006
EMBL· GenBank· DDBJ
MID45596.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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