A0A3T3G9E2 · A0A3T3G9E2_SALET
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- GeneaccD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids304 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- N6-carboxybiotinyl-L-lysyl-[protein] + acetyl-CoA = N6-biotinyl-L-lysyl-[protein] + malonyl-CoA
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 27 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 30 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 46 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 49 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A3T3G9E2
- Secondary accessions
Proteomes
Subcellular Location
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
Structure
Family & Domains
Features
Showing features for domain, zinc finger, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 23-292 | CoA carboxyltransferase N-terminal | |||
Zinc finger | 27-49 | C4-type | |||
Region | 283-304 | Disordered | |||
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length304
- Mass (Da)33,216
- Last updated2019-05-08 v1
- MD5 ChecksumCA7E352DAFF13840F2301A48E9EC8A13
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAHCWL010000010 EMBL· GenBank· DDBJ | EBU6915518.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHFAS010000009 EMBL· GenBank· DDBJ | EBV3761064.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHGTQ010000023 EMBL· GenBank· DDBJ | EBV9202373.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIGD010000007 EMBL· GenBank· DDBJ | EBW4104996.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIXO010000004 EMBL· GenBank· DDBJ | EBW6732060.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHKXZ010000010 EMBL· GenBank· DDBJ | EBX3355929.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHOXC010000010 EMBL· GenBank· DDBJ | EBY7385646.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHPAD010000010 EMBL· GenBank· DDBJ | EBY7627743.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHWIJ010000011 EMBL· GenBank· DDBJ | ECB0524778.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKLND010000002 EMBL· GenBank· DDBJ | ECT0409108.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKPQX010000003 EMBL· GenBank· DDBJ | ECU3483082.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKTKA010000009 EMBL· GenBank· DDBJ | ECV4805463.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALIQJ010000020 EMBL· GenBank· DDBJ | EDA0175841.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLSV010000009 EMBL· GenBank· DDBJ | EDA9402430.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALLTD010000008 EMBL· GenBank· DDBJ | EDA9437307.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMGJL010000004 EMBL· GenBank· DDBJ | EDH0979020.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMIHV010000010 EMBL· GenBank· DDBJ | EDH6429337.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAMJL010000009 EMBL· GenBank· DDBJ | HAC6917406.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARLP010000006 EMBL· GenBank· DDBJ | HAE2914223.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUC010000002 EMBL· GenBank· DDBJ | HAE3938643.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAARUZ010000002 EMBL· GenBank· DDBJ | HAE4047474.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLG010000005 EMBL· GenBank· DDBJ | HAE6000996.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASLQ010000003 EMBL· GenBank· DDBJ | HAE6030155.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAASRW010000005 EMBL· GenBank· DDBJ | HAE6746980.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAATPN010000003 EMBL· GenBank· DDBJ | HAE9561125.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAUAM010000026 EMBL· GenBank· DDBJ | HAF0863434.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RSGD01000006 EMBL· GenBank· DDBJ | MID45550.1 EMBL· GenBank· DDBJ | Genomic DNA |