A0A3S5Y9B8 · A0A3S5Y9B8_RHOH1
- ProteinPolyphosphate kinase
- Geneppk
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids739 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
Catalytic activity
- [phosphate](n) + ATP = [phosphate](n+1) + ADP
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 97 | ATP (UniProtKB | ChEBI) | |||
Binding site | 430 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 460 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 490 | Phosphohistidine intermediate | |||
Binding site | 523 | ATP (UniProtKB | ChEBI) | |||
Binding site | 619 | ATP (UniProtKB | ChEBI) | |||
Binding site | 647 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | polyphosphate kinase complex | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | polyphosphate kinase activity | |
Biological Process | phosphorylation | |
Biological Process | polyphosphate biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyphosphate kinase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Nocardiaceae > Prescottella
Accessions
- Primary accessionA0A3S5Y9B8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Post-translational modification
An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-55 | Disordered | |||
Compositional bias | 7-26 | Basic and acidic residues | |||
Domain | 59-164 | Polyphosphate kinase N-terminal | |||
Domain | 173-355 | Polyphosphate kinase middle | |||
Domain | 385-551 | Polyphosphate kinase C-terminal | |||
Domain | 558-724 | Polyphosphate kinase C-terminal | |||
Region | 716-739 | Disordered | |||
Compositional bias | 719-739 | Basic and acidic residues | |||
Sequence similarities
Belongs to the polyphosphate kinase 1 (PPK1) family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length739
- Mass (Da)81,954
- Last updated2019-04-10 v1
- MD5 Checksum1D26BC40D78FE350203024C6ECDF0D40
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 7-26 | Basic and acidic residues | |||
Compositional bias | 719-739 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN563149 EMBL· GenBank· DDBJ | CBH49135.1 EMBL· GenBank· DDBJ | Genomic DNA |