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A0A3S5Y9B8 · A0A3S5Y9B8_RHOH1

Function

function

Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

1739100200300400500600700
Type
IDPosition(s)Description
Binding site97ATP (UniProtKB | ChEBI)
Binding site430Mg2+ (UniProtKB | ChEBI)
Binding site460Mg2+ (UniProtKB | ChEBI)
Active site490Phosphohistidine intermediate
Binding site523ATP (UniProtKB | ChEBI)
Binding site619ATP (UniProtKB | ChEBI)
Binding site647ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentpolyphosphate kinase complex
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpolyphosphate kinase activity
Biological Processphosphorylation
Biological Processpolyphosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyphosphate kinase
  • EC number
  • Alternative names
    • ATP-polyphosphate phosphotransferase
    • Polyphosphoric acid kinase

Gene names

    • Name
      ppk
    • Ordered locus names
      REQ_31320

Organism names

Accessions

  • Primary accession
    A0A3S5Y9B8

Proteomes

Subcellular Location

PTM/Processing

Post-translational modification

An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-55Disordered
Compositional bias7-26Basic and acidic residues
Domain59-164Polyphosphate kinase N-terminal
Domain173-355Polyphosphate kinase middle
Domain385-551Polyphosphate kinase C-terminal
Domain558-724Polyphosphate kinase C-terminal
Region716-739Disordered
Compositional bias719-739Basic and acidic residues

Sequence similarities

Belongs to the polyphosphate kinase 1 (PPK1) family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    739
  • Mass (Da)
    81,954
  • Last updated
    2019-04-10 v1
  • MD5 Checksum
    1D26BC40D78FE350203024C6ECDF0D40
MSNGRALERRTDSDRSAEDGSDSDRTRPAGIGHSAIIPTAPPAATPTGSPDGGLPSARYLNRELSWLDFNSRVLALAEDTSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDETGLSVRSADGLSPREQLALIGSRTQEISYKHARVFLDSVRPALADEGISIIGWSDLDSEERTRLSAHFHEQVFPVLTPLAVDPAHPFPYISGLSLNLAVTVKDAATGGEHFARVKVPDNVDRFVRVTRTGDTPGAIAAFLPTEDLIAAHLDVLFPGMEVVEHHAFRVTRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEVADDMTEHMLELLLRELDVDPGDVIQVPGLLDLSSLWQVYGVDRPNLKDAPFVPATHPAFGERETPKSVFSTLRDGDVLVQHPYDSFSTSVQRFIEQAAADPQVLAIKQTLYRTSGDSPIVNALVAAAEAGKQVVALVEIKARFDEQANIKWARKLEQAGVHVVYGLVGLKTHCKTCLVVRREGSTIRRYCHIGTGNYNPKTARLYEDVGLLTAAPEIGADLTDLFNSLTGYSRKSQYRNLLVAPYGVRAGIIARIESEIEHRKAGREAGIRLKANALVDEQVIDALYRASQAGVPVRIVVRGICALKPGVPGLSENIEVRSILGRFLEHSRIMHFQGSNEFWIGSADMMHRNLDRRVEVMAQVKDPRLTRQLDEIFDSALDPTTRCWVLQSDGSWQAAPARGEKVREHQEEMMRRRRSTNS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias7-26Basic and acidic residues
Compositional bias719-739Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FN563149
EMBL· GenBank· DDBJ
CBH49135.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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