A0A3S5Y4T4 · A0A3S5Y4T4_RHOH1
- Protein2-oxoglutarate dehydrogenase SucA
- GenesucA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1256 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- N6-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H+ = N6-[(R)-S8-succinyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2
Cofactor
Protein has several cofactor binding sites:
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; succinyl-CoA from 2-oxoglutarate (dehydrogenase route): step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | oxoglutarate dehydrogenase complex | |
Molecular Function | dihydrolipoyllysine-residue succinyltransferase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | oxoglutarate dehydrogenase (succinyl-transferring) activity | |
Molecular Function | thiamine pyrophosphate binding | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Nocardiaceae > Prescottella
Accessions
- Primary accessionA0A3S5Y4T4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 74-134 | Disordered | |||
Compositional bias | 77-109 | Pro residues | |||
Coiled coil | 815-842 | ||||
Domain | 905-1101 | Transketolase-like pyrimidine-binding | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,256
- Mass (Da)137,143
- Last updated2019-04-10 v1
- MD5 Checksum00FC615BCA88D3A376BEBCCF3E6FB579
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 77-109 | Pro residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN563149 EMBL· GenBank· DDBJ | CBH47550.1 EMBL· GenBank· DDBJ | Genomic DNA |