A0A3S2TKB2 · A0A3S2TKB2_9GAMM

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

TypeIDPosition(s)Description
Site10Important for substrate specificity
Active site68Proton acceptor
Site69Important for substrate specificity
Site151Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • ORF names
      EMM73_10990

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • yqf_1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Chromatiales > Chromatiaceae > Rheinheimera

Accessions

  • Primary accession
    A0A3S2TKB2

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    187
  • Mass (Da)
    20,554
  • Last updated
    2019-04-10 v1
  • Checksum
    D8DF68B8BE8DC434
MIALASASPRRRELLAQLQQDFVLVKGEIDETQLAGETADQYVLRLAEQKAQAGYQSQLLPLPTLGADTIVQVDELVLGKPVDLADFKRMMMLLSGRSHWVKTAVAIATAQGLVSTTVATKVWFKALSEQEILWYWTTGEPVDKAGGYGIQGLAGQFVQRIDGSYFAVVGLPLYETAQLLQTLKDRQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RZUF01000014
EMBL· GenBank· DDBJ
RVT45983.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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