A0A3S2TKB2 · A0A3S2TKB2_9GAMM
- ProteindTTP/UTP pyrophosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids187 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Catalytic activity
- H2O + UTP = diphosphate + H+ + UMP
Cofactor
Features
Showing features for site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 10 | Important for substrate specificity | ||||
Sequence: R | ||||||
Active site | 68 | Proton acceptor | ||||
Sequence: D | ||||||
Site | 69 | Important for substrate specificity | ||||
Sequence: T | ||||||
Site | 151 | Important for substrate specificity | ||||
Sequence: Q |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | dTTP diphosphatase activity | |
Molecular Function | UTP diphosphatase activity | |
Biological Process | nucleotide metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedTTP/UTP pyrophosphatase
- EC number
- Short namesdTTPase/UTPase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Chromatiales > Chromatiaceae > Rheinheimera
Accessions
- Primary accessionA0A3S2TKB2
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length187
- Mass (Da)20,554
- Last updated2019-04-10 v1
- ChecksumD8DF68B8BE8DC434