A0A3S2MBI5 · A0A3S2MBI5_ORYJA

Function

function

Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentegg coat
Cellular Componentextracellular region
Cellular Componentplasma membrane
Molecular Functionstructural constituent of egg coat
Biological Processbinding of sperm to zona pellucida
Biological Processegg coat formation
Biological Processpositive regulation of acrosome reaction

Names & Taxonomy

Protein names

  • Recommended name
    Zona pellucida sperm-binding protein 3

Gene names

    • ORF names
      OJAV_G00056930

Organism names

  • Taxonomic identifier
  • Strain
    • RS831
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Atherinomorphae > Beloniformes > Adrianichthyidae > Oryziinae > Oryzias

Accessions

  • Primary accession
    A0A3S2MBI5

Proteomes

Subcellular Location

Zona pellucida
Cell membrane
; Single-pass type I membrane protein

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-21
ChainPRO_502571036322-421Zona pellucida sperm-binding protein 3

Post-translational modification

Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.

Keywords

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region52-73Disordered
Domain85-345ZP
Region373-399Disordered

Domain

The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.

Sequence similarities

Belongs to the ZP domain family. ZPC subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    421
  • Mass (Da)
    45,885
  • Last updated
    2019-04-10 v1
  • Checksum
    653ACA2B8C897B5E
MMKFTAVCLVVLALLDGFCDAQTGFGKPAYPPPGSKKPPQDPVQQKLIPEKELTWKYPADPQPEPKPVGPLEQRYPVPAATVAVDCREDLAHVEAKKDLFGIGQFIDPADLTLGKCPAVAEDPSAQVLIFQSALQDCGSSLTMTEDSLVYTFTLNYNPQALGSAPVVRTSQAVVIVECHYPRKHNVSSLALDPLWVPFSAAKMAEEFLYFSLKLTTDDFQFERPSYQYFLGDMIHIEATVKQYFHVPLRVYVDRCVATLSPDANSSPSYAFIDNFGCMLDGRITGSDSKFVSRPAENKLNFQLEAFRFQGADSGMIYITCHVKATSAAYPLDAEHKACSYVNGWREVSGADPVCAPCESSGFTAHTNTAVSPGTSIISGGGHGSGKPSDPSRKVRAASKSEVLEWQGDVTLGPIPIEERRI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM012442
EMBL· GenBank· DDBJ
RVE71953.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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