A0A3S0P2L9 · A0A3S0P2L9_9BACI
- ProteinMethionine--tRNA ligase
- GenemetG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids656 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Catalytic activity
- ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | methionine-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Biological Process | methionyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Lysinibacillus
Accessions
- Primary accessionA0A3S0P2L9
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for motif, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 299-303 | 'KMSKS' region | ||||
Sequence: KMSKS | ||||||
Domain | 556-656 | TRNA-binding | ||||
Sequence: DFMKVDLRVATVIECEPVPKANKLLKLQVDLGYEKRQVVSGIAEYYKPDELIGQKVIVVANLKPVKLRGELSQGMILAGSHDGVLKLATVDPNLANGAKVK |
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length656
- Mass (Da)75,539
- Last updated2019-04-10 v1
- Checksum103606295D66B9B0