A0A3S0L088 · A0A3S0L088_9PROT
- ProteinBifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids361 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 44 | Nucleophile; methyl group acceptor from methylphosphotriester | ||||
Sequence: C | ||||||
Binding site | 44 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 48 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 75 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 78 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Active site | 332 | Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | methylated-DNA-[protein]-cysteine S-methyltransferase activity | |
Molecular Function | sequence-specific DNA binding | |
Molecular Function | zinc ion binding | |
Biological Process | DNA repair | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Azospirillaceae > Azospirillum
Accessions
- Primary accessionA0A3S0L088
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 94-194 | HTH araC/xylS-type | ||||
Sequence: AQACRRIEAAVKDGEPVPSLADLAAQAGLSPFHYHRVFKAIAGVTPKGFASACKTALARTGLAAGKSVTETIYDAGYSSSSRFYDGATARLGMRPSDYRAG |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length361
- Mass (Da)38,266
- Last updated2019-04-10 v1
- ChecksumE10F03E7A3B4C107
Keywords
- Technical term