A0A3S0IY56 · A0A3S0IY56_STEMA
- ProteinThreonylcarbamoyl-AMP synthase
- GenetsaC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids196 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO3-/CO2 and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
Catalytic activity
- ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | double-stranded RNA binding | |
Molecular Function | L-threonylcarbamoyladenylate synthase | |
Biological Process | tRNA threonylcarbamoyladenosine modification |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThreonylcarbamoyl-AMP synthase
- EC number
- Short namesTC-AMP synthase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Stenotrophomonas > Stenotrophomonas maltophilia group
Accessions
- Primary accessionA0A3S0IY56
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 13-196 | YrdC-like | ||||
Sequence: ELTLDSAVATLRAGGVIAYPTEAVWGLGCDPSHEAAVHMVLRLKQRPIEKGMILVAAELAQLEGWVRLQALPDARQRAVLASWPGANTWILPAGPRAQRWVTGEHSGIAVRISSHPLVAELCRAWGGPLVSTSANLAGEPPARSREELDPRLLRLLDGILDGQTGGLAQPTPIRDALSGNVLRS |
Sequence similarities
Belongs to the SUA5 family. TsaC subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length196
- Mass (Da)20,827
- Last updated2019-04-10 v1
- Checksum82B5B1F710A5BEDC