A0A3S0HB28 · A0A3S0HB28_STEMA

Function

function

Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N6-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.
Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenylosuccinate lyase
  • EC number
  • Short names
    ASL
  • Alternative names
    • Adenylosuccinase

Gene names

    • ORF names
      EKL94_21505

Organism names

Accessions

  • Primary accession
    A0A3S0HB28

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-312Fumarate lyase N-terminal
Domain331-445Adenylosuccinate lyase PurB C-terminal

Sequence similarities

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    455
  • Mass (Da)
    49,632
  • Last updated
    2019-04-10 v1
  • Checksum
    C6457C89A97FEC2F
MSDSALLALSPLDGRYAGKVDALRPIFSEYGLIKARITVEVEWLLALAAEPGIVELAPFSDAAVARLRALAASFSPAQAARVKEIERTTNHDVKAVEYFIKEQLKDDAELAPALEFVHFACTSEDINNLSYGLMLEQARREVLLPTLDGIASSLRTLAHAQAGQPMLSRTHGQTASPTTLGKELANVVARLERQRKQIAAVELTGKINGAVGNYNAHIASYPDVDWPAFAERFVTGLGLVFNPYTTQIEPHDNIAEIGDAARRANIILIDLARDIWGYVSLGYFKQRLKEGEVGSSTMPHKVNPIDFENAEGNFGIANALFEHFSAKLPISRWQRDLTDSTVLRALGTAFGHSQVALDSLAKGLGKLEVNPQRLDADLDAAWEVLAEAVQTVMRRHGLPNPYEQLKALTRGQGITAESMRAFVQGLELPADAKQRLLEMTPGSYTGLAESLAKKI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RXLZ01000107
EMBL· GenBank· DDBJ
RTQ82781.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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