A0A3R7FIH4 · A0A3R7FIH4_9EURY

  • Protein
    Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)
  • Gene
    uppS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site37
Binding site37Mg2+ (UniProtKB | ChEBI)
Binding site38-41substrate
Binding site50substrate
Binding site54substrate
Binding site82-84substrate
Active site85Proton acceptor
Binding site86substrate
Binding site88substrate
Binding site207substrate
Binding site213-215substrate
Binding site226Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmagnesium ion binding
Molecular Functionprenyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)
  • EC number
  • Alternative names
    • Undecaprenyl diphosphate synthase
      (UDS
      )
    • Undecaprenyl pyrophosphate synthase
      (UPP synthase
      )

Gene names

    • Name
      uppS
    • ORF names
      DVK01_02095

Organism names

  • Taxonomic identifier
  • Strain
    • Atlit-120R
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloarculaceae > Haloarcula

Accessions

  • Primary accession
    A0A3R7FIH4

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the UPP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    308
  • Mass (Da)
    35,274
  • Last updated
    2019-04-10 v1
  • Checksum
    C39107DC5076215E
MITTMLSRGKRLGYAAYERLLQWELSGTPDHVAVIQDGNRRYAEKQGTKKQKGHTEGAETTEALLNWCDELDIREVTLYAFSTENFDRDPEEREHIFDLVEQKLRTFADADRVHEAGVCIRAIGETEMLPERVRDAIDYAEGRTAQYDQLNLNVALAYGGRAELLGAARDIATAVEDGTLDPTDVSAETIEERLYEGPTRDVDLIVRTGGDERTSNFLPWHANGNEAATFFCTPYWPEFRKVDFLRAIRTYQNREQSWRTTRAERSLALVRAIEQSELPTAKRMLGRFRDALPSTERERLDEEYDLAD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QPLN01000001
EMBL· GenBank· DDBJ
RLM39372.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp