A0A3Q8TYG2 · A0A3Q8TYG2_9PSED
- ProteinPyruvate dehydrogenase E1 component
- GeneaceE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids881 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
Catalytic activity
- H+ + N6-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate = CO2 + N6-[(R)-S8-acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]
Cofactor
Protein has several cofactor binding sites:
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | pyruvate dehydrogenase (acetyl-transferring) activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyruvate dehydrogenase E1 component
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A3Q8TYG2
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 134-287 | Transketolase N-terminal | ||||
Sequence: FQGHASPGVYARAFMEGRINEDQMNNFRQEVDGNGLSSYPHPWLMPDFWQFPTVSMGLGPIQAIYQARFMKYLEARGFIPAGKQKVWCFMGDGECDEPESLGAIALAGREKLDNLIFVINCNLQRLDGPVRGNGKIIQELEGVFRGGGWNVNKV | ||||||
Domain | 472-691 | Pyruvate dehydrogenase E1 component middle | ||||
Sequence: TLKAILDGSGDREISTTMAFVRILAQLVKDKEIGQRIVPIIPDEARTFGMEGMFRQLGIYSSVGQLYEPVDKDQVMFYREDKKGQILEEGINEAGAMSSFIAAGTSYSCHNQPMLPFYIFYSMFGFQRIGDLAWAAGDSRTRGFLIGGTAGRTTLNGEGLQHEDGHSHMMAGTIPNCRTYDPTYGYELAVIIQDGMKKMTEEQQDIFYYITVMNESYQQP |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length881
- Mass (Da)99,272
- Last updated2019-04-10 v1
- ChecksumBC923520174DAF57
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP034338 EMBL· GenBank· DDBJ | AZL66558.1 EMBL· GenBank· DDBJ | Genomic DNA |