A0A3Q7T877 · A0A3Q7T877_VULVU
- ProteinBPI fold-containing family A member 1
- GeneBPIFA1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids255 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular space | |
Molecular Function | lipid binding | |
Biological Process | antibacterial humoral response | |
Biological Process | antimicrobial humoral immune response mediated by antimicrobial peptide | |
Biological Process | defense response to virus | |
Biological Process | immune response in nasopharyngeal-associated lymphoid tissue | |
Biological Process | innate immune response | |
Biological Process | multicellular organismal-level water homeostasis | |
Biological Process | negative regulation of single-species biofilm formation in or on host organism | |
Biological Process | regulation of sodium ion transmembrane transport | |
Biological Process | surfactant homeostasis |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended nameBPI fold-containing family A member 1
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Vulpes
Accessions
- Primary accessionA0A3Q7T877
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-23 | |||||
Sequence: MFQIGGLIVFCGLLAQTTTLLEA | ||||||
Chain | PRO_5018617116 | 24-255 | BPI fold-containing family A member 1 | |||
Sequence: LSLPLEHTLFLEATPGQDPSPTDLAGDLTNGLSSGLLSGGLLDILENLPLLNILKTGGGTSGGLLGGLLGKVTSVVPLLDSIIELKITNPQLLELGLVQSPDGHRLYVTIPLGIVLNVNTPLTSSLAKLAMKLNITAEILAVKNDQGKIHLILGDCTHSPGSLQISLLNGFAPLPVQSLVDSLSSFLNKVLPELVQGEVCPLVNEVLSELDVTLVHSIAELLIHGLEFVIKV |
Interaction
Subunit
Monomer. Interacts (via N-terminus) with SCNN1B, a subunit of the heterotrimeric epithelial sodium channel (ENaC); this inhibits proteolytic activation of ENaC.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 64-233 | Lipid-binding serum glycoprotein N-terminal | ||||
Sequence: LLDILENLPLLNILKTGGGTSGGLLGGLLGKVTSVVPLLDSIIELKITNPQLLELGLVQSPDGHRLYVTIPLGIVLNVNTPLTSSLAKLAMKLNITAEILAVKNDQGKIHLILGDCTHSPGSLQISLLNGFAPLPVQSLVDSLSSFLNKVLPELVQGEVCPLVNEVLSEL |
Sequence similarities
Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length255
- Mass (Da)26,700
- Last updated2019-04-10 v1
- ChecksumB78B23575362821C
Keywords
- Technical term