A0A3Q3KJ79 · A0A3Q3KJ79_9TELE
- ProteinPhosphatidylinositol-3,5-bisphosphate 3-phosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids583 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-3-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 268-271 | substrate | ||||
Sequence: NKAK | ||||||
Binding site | 293-294 | substrate | ||||
Sequence: NI | ||||||
Active site | 355 | Phosphocysteine intermediate | ||||
Sequence: C | ||||||
Binding site | 355-361 | substrate | ||||
Sequence: CSDGWDR |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | |
Molecular Function | phosphatidylinositol-3-phosphate phosphatase activity | |
Biological Process | lipid metabolic process |
Keywords
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphatidylinositol-3,5-bisphosphate 3-phosphatase
- EC number
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Anabantaria > Synbranchiformes > Mastacembelidae > Mastacembelus
Accessions
- Primary accessionA0A3Q3KJ79
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-29 | |||||
Sequence: MLSGVHASFCSSSLLSLLSPMLHSQRVTA | ||||||
Chain | PRO_5030080819 | 30-583 | Phosphatidylinositol-3,5-bisphosphate 3-phosphatase | |||
Sequence: YKTFSNFSYLLFCVCVYAVKDVMYICPFSGLVSGTLTITDYKFYFTSMETSPFVLDVNLGAISRMETITVSNQGENTKGLELVCKVPLIHPHQNESISDSLFAFLYKEQFPVDGWKVYDPVAEYRRQGLPNESWAISKINITFELCDTYPSILVIPTNITDEDIKRVSVFRAKHRIPVLSWIHPESQATIIRCSQPLVGPTDRRCKEDERLLQIIMDANAQSHKLTIFDARQSSVAVTNKAKDGGYESESFYTNVELNFLEIPNIHVMRESLRKMKDVVYPTIDEAHWHSAIDQTHWLEYIRLLLAGAAKIADKLESGKTSVVVHCSDGWDRTTQLTSLAMLMLDSYYRTLCGFQVLVEKEWISFGHKFSARVGHGDENHANSERSPLFVQFIDCVWQMTRQFPAAFQFNELFLMTVLDHLYSCLFGTFLYNSEAERAAKEVQTKTVSLWSYINSQPEDFSNPFYVDYEHHVLYPLVSSRHLELWTSYYARWNPRMRPQVPVHQTLKELLILRAELQRKVEELQKEAFSQSPSSSSEHSPSHTHATGTPLHTGV |
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 143-518 | Myotubularin phosphatase | ||||
Sequence: GWKVYDPVAEYRRQGLPNESWAISKINITFELCDTYPSILVIPTNITDEDIKRVSVFRAKHRIPVLSWIHPESQATIIRCSQPLVGPTDRRCKEDERLLQIIMDANAQSHKLTIFDARQSSVAVTNKAKDGGYESESFYTNVELNFLEIPNIHVMRESLRKMKDVVYPTIDEAHWHSAIDQTHWLEYIRLLLAGAAKIADKLESGKTSVVVHCSDGWDRTTQLTSLAMLMLDSYYRTLCGFQVLVEKEWISFGHKFSARVGHGDENHANSERSPLFVQFIDCVWQMTRQFPAAFQFNELFLMTVLDHLYSCLFGTFLYNSEAERAAKEVQTKTVSLWSYINSQPEDFSNPFYVDYEHHVLYPLVSSRHLELWTSYY | ||||||
Domain | 324-371 | Tyrosine specific protein phosphatases | ||||
Sequence: THWLEYIRLLLAGAAKIADKLESGKTSVVVHCSDGWDRTTQLTSLAML | ||||||
Region | 552-583 | Disordered | ||||
Sequence: LQKEAFSQSPSSSSEHSPSHTHATGTPLHTGV | ||||||
Compositional bias | 555-583 | Polar residues | ||||
Sequence: EAFSQSPSSSSEHSPSHTHATGTPLHTGV |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length583
- Mass (Da)66,731
- Last updated2021-06-02 v2
- ChecksumD4D0C263C2C9ECF9
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A3Q3KTE4 | A0A3Q3KTE4_9TELE | 695 | |||
A0A7N8XPE3 | A0A7N8XPE3_9TELE | 493 | |||
A0A3Q3KJH3 | A0A3Q3KJH3_9TELE | 664 | |||
A0A3Q3KJ94 | A0A3Q3KJ94_9TELE | 666 | |||
A0A3Q3KHD8 | A0A3Q3KHD8_9TELE | 672 | |||
A0A3Q3KGU4 | A0A3Q3KGU4_9TELE | 565 | |||
A0A3Q3KGX3 | A0A3Q3KGX3_9TELE | 644 | |||
A0A7N8WVX2 | A0A7N8WVX2_9TELE | 558 | |||
A0A7N8XKH8 | A0A7N8XKH8_9TELE | 582 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 555-583 | Polar residues | ||||
Sequence: EAFSQSPSSSSEHSPSHTHATGTPLHTGV |
Keywords
- Technical term