A0A3Q3DCH7 · A0A3Q3DCH7_HIPCM

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site264
Active site321
Active site345
Binding site385Ca2+ (UniProtKB | ChEBI)
Binding site387Ca2+ (UniProtKB | ChEBI)
Binding site433Ca2+ (UniProtKB | ChEBI)
Binding site438Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchromosome
Cellular Componentcollagen-containing extracellular matrix
Cellular Componentcytosol
Cellular Componentextracellular region
Cellular Componentmitochondrion
Cellular Componentnucleus
Cellular Componentplasma membrane
Molecular FunctionGTP binding
Molecular Functionmetal ion binding
Molecular Functionpeptidase activity
Molecular Functionprotein-glutamine gamma-glutamyltransferase activity
Biological Processnervous system development
Biological Processpeptide cross-linking
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-glutamine gamma-glutamyltransferase 2
  • EC number
  • Alternative names
    • Isopeptidase TGM2
    • Protein-glutamine deamidase TGM2
    • Protein-glutamine dopaminyltransferase TGM2
    • Protein-glutamine histaminyltransferase TGM2
    • Protein-glutamine noradrenalinyltransferase TGM2

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Syngnathiaria > Syngnathiformes > Syngnathoidei > Syngnathidae > Hippocampus

Accessions

  • Primary accession
    A0A3Q3DCH7

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain256-348Transglutaminase-like

Sequence similarities

Belongs to the transglutaminase superfamily. Transglutaminase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    674
  • Mass (Da)
    74,681
  • Last updated
    2019-04-10 v1
  • Checksum
    9B85A8AC2044F152
SAQTASLWCDFNNTDHYTDLNGVDRLIVRRGQPFNISLYLRSGSYQPGLSSLECIAETGPQPSEQYGTRASFGLSANIDTSRWSAAVVSPPGDTVALSLCAAPDAPIGRYILTMGRSARIEFILLFNPWCSGDAVYLDNKESLEEYVLSQDGIIFQGDVNHPIATPWNFGQFESGILDVCLRILDMNPKCLRNPGKDCSGRRNPIYVSRVVSAMVNCNDDKGVLLGNWTNDFDGGVSPMFWKGSVEILRNWQTQACQPVRFGQCWVFAAVACSISRALGIPCRVVTNYYSAHDVNRNLTIERYVNENGELVRSKEMIWNYHCWVESWMTRPDLTGSAYNGWQASDPTPQEKSDGVFCCGPIPVRAIKEGELMYKYDAPFVFAEVNADVITTMMKKDGSTSKVTSTQLVGKKISTKGIGSDYREDITHLYKHPEGSDEEREAFKKANHQNKLLQTKESEGLNVSIKVSPEMKKGCDFEVFAVVTNNSSSDKKCRLLFGSCAVSYNGFQGGNCGFKDLLNVELSPGGARKVPLRLNYSKYGGLLTEDNMIRLAALLFDYATREATLAVRNIVLDNPEIQVRILGEPKENRKLAAEITLKNPLPEPLENCCFSMEGANLTGGRVISERLRSAVGPGEDAKVKMYFTPTHSGLRKLVVDFDSSKLCHVKGYKNVIIGK

Genome annotation databases

Similar Proteins

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