A0A3Q2IDL5 · A0A3Q2IDL5_HORSE

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell surface
Cellular Componentfocal adhesion
Cellular Componentintegrin complex
Cellular Componentlamellipodium
Cellular Componentmelanosome
Cellular Componentruffle membrane
Cellular Componentsynapse
Molecular Functioncollagen binding involved in cell-matrix adhesion
Molecular Functionfibronectin binding
Molecular Functionintegrin binding
Molecular Functionprotein kinase binding
Biological Processcell-cell adhesion
Biological Processintegrin-mediated signaling pathway
Biological Processmuscle organ development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Integrin beta

Gene names

    • Name
      ITGB1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Thoroughbred
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Equidae > Equus

Accessions

  • Primary accession
    A0A3Q2IDL5

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Single-pass type I membrane protein
Cell projection, invadopodium membrane
; Single-pass type I membrane protein
Cell projection, lamellipodium
Cell projection, ruffle membrane
; Single-pass type I membrane protein
Melanosome

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane736-758Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-27
ChainPRO_501861921128-808Integrin beta
Disulfide bond42↔52
Disulfide bond45↔82
Disulfide bond55↔71
Disulfide bond214↔220
Disulfide bond268↔308
Disulfide bond442↔698
Disulfide bond469↔473
Disulfide bond484↔496
Disulfide bond493↔532
Disulfide bond498↔507
Disulfide bond509↔523
Disulfide bond538↔543
Disulfide bond540↔575
Disulfide bond545↔560
Disulfide bond562↔567
Disulfide bond581↔586
Disulfide bond583↔614
Disulfide bond588↔597
Disulfide bond599↔606
Disulfide bond620↔625
Disulfide bond622↔668
Disulfide bond627↔637
Disulfide bond640↔643
Disulfide bond647↔656
Disulfide bond653↔730
Disulfide bond672↔706

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain33-83PSI
Domain41-471Integrin beta subunit VWA
Compositional bias82-105Basic and acidic residues
Region82-112Disordered
Domain647-735Integrin beta subunit tail
Domain759-805Integrin beta subunit cytoplasmic

Sequence similarities

Belongs to the integrin beta chain family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    808
  • Mass (Da)
    89,547
  • Last updated
    2019-04-10 v1
  • MD5 Checksum
    B221D127A83610EA9DA676ED9C4F36DF
MANREFQMNLQLVFWIGLISSICYVFGQADENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCHPDDIENPRGSKDIKKNKNVTNRSKGTAEKLQPEDITQIQPQQLVLQLRSGEPQTFALKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTDKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENDVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENSKLPEGVTINYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPNKNSETIKIKPLGFTEEVEVVLQFICECECQSEGVPSSPRCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTTSCMATNGQICNGRGICECGACKCTDPKFQGPTCEMCQTCLGVCAEHKECVQCRAFNKGEKKDTCAQECSHFNITKVENRDKLPQPGQVDPLSHCKEKDVDDCWFYFTYSVNGNNEAIVHVVETPECPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTQENPIYKSPINNFKNPNYGRKAGL

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
F6UR46F6UR46_HORSEITGB1798
A0A9L0TG92A0A9L0TG92_HORSEITGB1819
A0A9L0SKP9A0A9L0SKP9_HORSEITGB1808
A0A9L0SCX1A0A9L0SCX1_HORSEITGB1809

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias82-105Basic and acidic residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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