A0A3Q2IDL5 · A0A3Q2IDL5_HORSE
- ProteinIntegrin beta
- GeneITGB1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids808 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cell surface | |
Cellular Component | focal adhesion | |
Cellular Component | integrin complex | |
Cellular Component | lamellipodium | |
Cellular Component | melanosome | |
Cellular Component | ruffle membrane | |
Cellular Component | synapse | |
Molecular Function | collagen binding involved in cell-matrix adhesion | |
Molecular Function | fibronectin binding | |
Molecular Function | integrin binding | |
Molecular Function | protein kinase binding | |
Biological Process | cell-cell adhesion | |
Biological Process | integrin-mediated signaling pathway | |
Biological Process | muscle organ development |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameIntegrin beta
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Equidae > Equus
Accessions
- Primary accessionA0A3Q2IDL5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Cell projection, invadopodium membrane ; Single-pass type I membrane protein
Cell projection, ruffle membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 736-758 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-27 | ||||
Chain | PRO_5018619211 | 28-808 | Integrin beta | ||
Disulfide bond | 42↔52 | ||||
Disulfide bond | 45↔82 | ||||
Disulfide bond | 55↔71 | ||||
Disulfide bond | 214↔220 | ||||
Disulfide bond | 268↔308 | ||||
Disulfide bond | 442↔698 | ||||
Disulfide bond | 469↔473 | ||||
Disulfide bond | 484↔496 | ||||
Disulfide bond | 493↔532 | ||||
Disulfide bond | 498↔507 | ||||
Disulfide bond | 509↔523 | ||||
Disulfide bond | 538↔543 | ||||
Disulfide bond | 540↔575 | ||||
Disulfide bond | 545↔560 | ||||
Disulfide bond | 562↔567 | ||||
Disulfide bond | 581↔586 | ||||
Disulfide bond | 583↔614 | ||||
Disulfide bond | 588↔597 | ||||
Disulfide bond | 599↔606 | ||||
Disulfide bond | 620↔625 | ||||
Disulfide bond | 622↔668 | ||||
Disulfide bond | 627↔637 | ||||
Disulfide bond | 640↔643 | ||||
Disulfide bond | 647↔656 | ||||
Disulfide bond | 653↔730 | ||||
Disulfide bond | 672↔706 | ||||
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 33-83 | PSI | |||
Domain | 41-471 | Integrin beta subunit VWA | |||
Compositional bias | 82-105 | Basic and acidic residues | |||
Region | 82-112 | Disordered | |||
Domain | 647-735 | Integrin beta subunit tail | |||
Domain | 759-805 | Integrin beta subunit cytoplasmic | |||
Sequence similarities
Belongs to the integrin beta chain family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length808
- Mass (Da)89,547
- Last updated2019-04-10 v1
- MD5 ChecksumB221D127A83610EA9DA676ED9C4F36DF
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F6UR46 | F6UR46_HORSE | ITGB1 | 798 | ||
A0A9L0TG92 | A0A9L0TG92_HORSE | ITGB1 | 819 | ||
A0A9L0SKP9 | A0A9L0SKP9_HORSE | ITGB1 | 808 | ||
A0A9L0SCX1 | A0A9L0SCX1_HORSE | ITGB1 | 809 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 82-105 | Basic and acidic residues | |||
Keywords
- Technical term