A0A3Q2I6V8 · A0A3Q2I6V8_HORSE

  • Protein
    protein deglycase
  • Gene
    PARK7
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

Catalytic activity

  • N2-(1-hydroxy-2-oxoethyl)-GDP + H2O = glycolate + GDP + H+
  • N2-(1-hydroxy-2-oxoethyl)-GMP + H2O = glycolate + GMP + H+
  • N2-(1-hydroxy-2-oxoethyl)-GTP + H2O = glycolate + GTP + H+
  • N2-(1-hydroxy-2-oxoethyl)-dGTP + H2O = dGTP + glycolate + H+
  • N2-(1-hydroxy-2-oxopropyl)-GDP + H2O = lactate + GDP + H+
  • N2-(1-hydroxy-2-oxopropyl)-GMP + H2O = lactate + GMP + H+
  • N2-(1-hydroxy-2-oxopropyl)-GTP + H2O = lactate + GTP + H+
  • N2-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H+
  • N6-(1-hydroxy-2-oxoethyl)-L-lysyl-[protein] + H2O = glycolate + L-lysyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • N6-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein] + H2O = lactate + L-lysyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein] + H2O = L-arginyl-[protein] + glycolate + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] + H2O = lactate + L-arginyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein] + H2O = glycolate + L-cysteinyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein] + H2O = lactate + L-cysteinyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • an N2-(1-hydroxy-2-oxoethyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + glycolate + H+
  • an N2-(1-hydroxy-2-oxoethyl)-guanosine in RNA + H2O = a guanosine in RNA + glycolate + H+
  • an N2-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + lactate + H+
  • an N2-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O = a guanosine in RNA + lactate + H+

GO annotations

AspectTerm
Cellular Componentmembrane raft
Molecular Functionprotein deglycase activity
Biological Processautophagy
Biological Processsingle fertilization

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    protein deglycase
  • EC number
  • Alternative names
    • Maillard deglycase
    • Parkinsonism-associated deglycase
    • Protein DJ-1
    • Protein/nucleic acid deglycase DJ-1

Gene names

    • Name
      PARK7

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Thoroughbred
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Equidae > Equus

Accessions

  • Primary accession
    A0A3Q2I6V8

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Keywords

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-108DJ-1/PfpI

Sequence similarities

Belongs to the peptidase C56 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    200
  • Mass (Da)
    21,660
  • Last updated
    2019-04-10 v1
  • Checksum
    43548E9C3B3298EC
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTIAGLAGKDPVQCSRDVVICPDASLEDAKKQGPYDVVVLPGGNLGAQNLSESAAVKEILKEQEKRKGLIAAICAVDLGGNKTLWNSETACSSKSLCQKVFVPARSQQESVRHKHCSSALCLPWLPRPRGAFRLISSVERWALGILLSATGFRRRSLVLCRCPHVFEI

Computationally mapped potential isoform sequences

There are 6 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A9L0RX58A0A9L0RX58_HORSEPARK773
A0A5F5PFH0A0A5F5PFH0_HORSEPARK7169
A0A9L0R9C9A0A9L0R9C9_HORSEPARK7178
F6WPB4F6WPB4_HORSEPARK7208
A0A9L0SPI8A0A9L0SPI8_HORSEPARK7207
A0A9L0SBB9A0A9L0SBB9_HORSEPARK7233

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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