A0A3Q2I103 · A0A3Q2I103_HORSE

  • Protein
    GATOR complex protein NPRL3
  • Gene
    NPRL3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentGATOR1 complex
Cellular Componentlysosomal membrane
Molecular FunctionGTPase activator activity
Biological Processaorta morphogenesis
Biological Processcardiac muscle tissue development
Biological Processcellular response to amino acid starvation
Biological Processnegative regulation of TORC1 signaling
Biological Processroof of mouth development
Biological Processventricular septum development

Names & Taxonomy

Protein names

  • Recommended name
    GATOR complex protein NPRL3
  • Alternative names
    • Nitrogen permease regulator 3-like protein

Gene names

    • Name
      NPRL3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Thoroughbred
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Equidae > Equus

Accessions

  • Primary accession
    A0A3Q2I103

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region384-448Disordered
Compositional bias403-448Polar residues

Sequence similarities

Belongs to the NPR3 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    538
  • Mass (Da)
    60,080
  • Last updated
    2019-12-11 v2
  • Checksum
    1ED1FEC1524D1432
MLGLRCYCVYPLGATMSPWSLYGASLWGTWIRFSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQHALGQVSKTDPSPKRETPTMILFNVVFALRANADPSVISCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAVADANGGPQSPFHHILPKCKLARDLKEAYDSLCSSGVVRLHINSWLEVSFCLPHKIHYAAASLIPPEAIERSLKAIRPYHALLLLSDEKSLLGELPLDCSPALVRVIKTTSAVKNLQQLAQDADLALLQVFQLAAHLVYWGKAIIIYPLCENNVYMLSPNASVCLYSPLAEQFSRQFPSHDLPSVLAKFSLPVSLSEFRNPLAPPVQETQLIQMVVWMLQRRLLVQLHTYVCLMASPGEDEPRPREDDVPFTTRVGGRSLSTPNALSFGSPTSSDDMTLTSPSMDNSSAELLPSGDSPLNRRMTESLLASLSEHERAAILSVPAAQNPEDLRTFARLLHYFRGRHHLEEIMYNENTRRSQLLTLFDKFRSVLVVTTHEDPVIAVFQALLT

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A3Q2IAJ6A0A3Q2IAJ6_HORSENPRL3521

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias403-448Polar residues

Keywords

Genome annotation databases

Similar Proteins

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