A0A3Q2GXV6 · A0A3Q2GXV6_HORSE

  • Protein
    Hes family bHLH transcription factor 5
  • Gene
    HES5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular FunctionDNA-binding transcription repressor activity, RNA polymerase II-specific
Molecular Functionprotein dimerization activity
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding
Biological Processanterior/posterior pattern specification
Biological Processastrocyte differentiation
Biological ProcessBMP signaling pathway
Biological Processcamera-type eye development
Biological Processcartilage development
Biological Processcell adhesion
Biological Processcell maturation
Biological Processcentral nervous system myelination
Biological Processcomma-shaped body morphogenesis
Biological Processestablishment of epithelial cell polarity
Biological Processglial cell fate commitment
Biological Processinner ear auditory receptor cell differentiation
Biological Processinner ear receptor cell stereocilium organization
Biological Processmetanephric nephron tubule morphogenesis
Biological Processnegative regulation of astrocyte differentiation
Biological Processnegative regulation of inner ear auditory receptor cell differentiation
Biological Processnegative regulation of oligodendrocyte differentiation
Biological Processnegative regulation of stem cell differentiation
Biological Processneural tube development
Biological Processneuronal stem cell population maintenance
Biological ProcessNotch signaling pathway
Biological Processpositive regulation of BMP signaling pathway
Biological Processpositive regulation of Notch signaling pathway
Biological Processpositive regulation of receptor signaling pathway via JAK-STAT
Biological Processpositive regulation of smooth muscle cell proliferation
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processpositive regulation of tyrosine phosphorylation of STAT protein
Biological Processprotein-containing complex assembly
Biological Processregulation of epithelial cell proliferation
Biological Processregulation of myelination
Biological Processregulation of neurogenesis
Biological Processregulation of transcription by RNA polymerase II
Biological ProcessS-shaped body morphogenesis
Biological Processsmoothened signaling pathway
Biological Processspecification of loop of Henle identity
Biological Processtelencephalon development

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Hes family bHLH transcription factor 5

Gene names

    • Name
      HES5

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Thoroughbred
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Equidae > Equus

Accessions

  • Primary accession
    A0A3Q2GXV6

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain16-72BHLH
Domain88-119Orange
Compositional bias124-143Pro residues
Region124-164Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    164
  • Mass (Da)
    18,111
  • Last updated
    2019-04-10 v1
  • Checksum
    11FAC137E1F27D6D
MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSKAFAAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQRPPAAPAPPAKEPKAPGAAPAPALTPAKPAAAARQPACGLWRPW

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias124-143Pro residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help