A0A3Q2GXQ8 · A0A3Q2GXQ8_HORSE

  • Protein
    mitogen-activated protein kinase kinase kinase
  • Gene
    MAP3K10
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

1904100200300400500600700800900
TypeIDPosition(s)Description
Binding site125ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase kinase activity
Molecular Functionprotein serine kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    mitogen-activated protein kinase kinase kinase
  • EC number

Gene names

    • Name
      MAP3K10

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Thoroughbred
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Equidae > Equus

Accessions

  • Primary accession
    A0A3Q2GXQ8

Proteomes

Subcellular Location

Expression

Gene expression databases

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, coiled coil, region, compositional bias.

Type
IDPosition(s)Description
Domain16-81SH3
Domain98-366Protein kinase
Coiled coil391-444
Region490-769Disordered
Compositional bias525-539Polar residues
Compositional bias617-633Basic and acidic residues
Region785-904Disordered
Compositional bias882-896Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    904
  • Mass (Da)
    98,645
  • Last updated
    2023-09-13 v2
  • MD5 Checksum
    F6336E68835E33740694B9E28A5F0085
MEEEVGGAAKEWGATPAGPVWTAVFDYEAAGDEELTLRRGDRVQVLSQDWAVSGDEGWWTGRLPSGRVGVFPSNYVTPGPPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPERDPALTAEQVRQEARLFGALQHPNIIALRGACLSPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEAIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKPRVRKRRGNFKRSRLLKLREGGSHISLPSGFEHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDGGGGGSSGSSSGGSVTWGRSGPPKKEELVGGKKKGRTWGPSSTLQKERAGGEERLKALGEGSKQWSSSAPNLGKSPKHTPIAPGFASLNEMGKTVRAPLRERGRGHPLARRGAEPETNGGPFPRVGGGSGISLVPRGAGIPGKGDSQAPGCGVTPRGRGPCGEEDARTAPRGDSAVSLSEGPRGPGPAGVERGLSRLQRSSRRRRAAAACPPPRTAPRPTSRRRCRPSAPRGRPPRDPRPAAGGAASWPCWAAPRCWAPWAWAPTWPRRAPPTARSSGAGSTGSSSPAPAAARPPAPRAAATTPARAWRPRPPSCRCRPCPTATPRARCCAPTATRPRRPRPPRRPPRPRPAPTPWWTWSWRASRRTPASRSHPPTSRPRAP

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A9L0TE25A0A9L0TE25_HORSEMAP3K10931
A0A3Q2IAK9A0A3Q2IAK9_HORSEMAP3K10944
A0A9L0RDJ1A0A9L0RDJ1_HORSEMAP3K10322
A0A9L0TCQ1A0A9L0TCQ1_HORSEMAP3K10272

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias525-539Polar residues
Compositional bias617-633Basic and acidic residues
Compositional bias882-896Polar residues

Keywords

Genome annotation databases

Similar Proteins

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