A0A3Q1MFM9 · A0A3Q1MFM9_BOVIN

  • Protein
    Acylglycerol kinase, mitochondrial
  • Gene
    AGK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Catalytic activity

  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-sn-glycerol + ATP = 1-hexadecanoyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + ATP = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • N-(hexanoyl)sphing-4-enine + ATP = N-hexanoylsphing-4-enine 1-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.107 (UniProtKB | ENZYME | Rhea)
  • a 1-acyl-sn-glycerol + ATP = a 1-acyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a 2-acylglycerol + ATP = a 2-acyl-sn-glycerol 3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a monoacylglycerol + ATP = a monoacyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.94 (UniProtKB | ENZYME | Rhea)
  • an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.138 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Lipid metabolism; glycerolipid metabolism.

GO annotations

AspectTerm
Cellular Componentmitochondrial intermembrane space
Cellular Componentmitochondrion
Cellular ComponentTIM22 mitochondrial import inner membrane insertion complex
Molecular Functionacylglycerol kinase activity
Molecular FunctionATP-dependent diacylglycerol kinase activity
Molecular Functionceramide kinase activity
Biological Processceramide biosynthetic process
Biological Processglycerolipid metabolic process
Biological Processlipid phosphorylation
Biological Processprotein insertion into mitochondrial inner membrane

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acylglycerol kinase, mitochondrial
  • EC number
  • Alternative names
    • Multiple substrate lipid kinase

Gene names

    • Name
      AGK

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0A3Q1MFM9

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain146-200DAGKc
Region250-272Disordered

Sequence similarities

Belongs to the AGK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    421
  • Mass (Da)
    46,946
  • Last updated
    2019-04-10 v1
  • Checksum
    7D136E8602B9EC38
MTVFFKTLRNHWKKTTAGICLLTWGGHWVYGKHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACKGYFVVFMNCLVLETASSVLHDGWSRAVGRKTGRQGQGHLLCFMDTSVPLCSISFSDHNNKTSLSFSSRQATFSKIPIGFIPLGQTSSLSQTLFAESGNKVQRITDATLAIVKGETVPLDVLQIKGEKEQPVFALTGLRWGSFRDAGVSVSRYWYLGPLKTKAAHFFSTLKEWPQTHQASISYTGPTERPPSGAEETPPRPSLYRRILRRLASYWAQPQGALQEVNPEVWKEVQLSTLELSITTRNSQLDLASKEDFMNICMEPNTVSKGDFITIGSKKVRDPKLHVEGTECLQASRCTLLLPEGTGGAFSIDSEEYEAMPVEVKLLPRKLQFFCDPRKREQLLQSPAQ

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A6QR07A6QR07_BOVINAGK420
F6R5V8F6R5V8_BOVINAGK384
A0AAA9TL12A0AAA9TL12_BOVINAGK214
F6Q508F6Q508_BOVINAGK243

Keywords

Genome annotation databases

Similar Proteins

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