A0A3Q1LV32 · A0A3Q1LV32_BOVIN

  • Protein
    Succinyl-CoA:3-ketoacid-coenzyme A transferase
  • Gene
    OXCT1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

function

Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Catalytic activity

Pathway

Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1.

Features

Showing features for active site.

149050100150200250300350400450
TypeIDPosition(s)Description
Active site3445-glutamyl coenzyme A thioester intermediate

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionsuccinyl-CoA:3-oxo-acid CoA-transferase activity
Biological Processketone body catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinyl-CoA:3-ketoacid-coenzyme A transferase
  • EC number

Gene names

    • Name
      OXCT1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0A3Q1LV32

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Family & Domains

Sequence similarities

Belongs to the 3-oxoacid CoA-transferase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    490
  • Mass (Da)
    53,364
  • Last updated
    2019-04-10 v1
  • Checksum
    E3D5A3D5AB6DD7BA
MAALARLSSRLRFCASALSSAGVWSKGCICYFSTSTRHHTKFYTDPVEAVKDIPDGATILVGGFGLCGIPENLIGALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTSTGYGTLVQEGGSPIKYNKDGSIAIASKPREVREFKGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGSFAPEDIHIPKIYVHRLIKGEKYEKRIERLSIRKEEDIKTTSGKPGDNVRERIIKRAALEFEDGMYANLGIGIPLLASNYISPDMTVHLQSENGVLGLGPYPLKNEVDADLINAGKETVTVLPGASYFSSDESFAMIRGGHVNLTMLGAMQVSKYGDLANWMIPGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDSKKGLTLIELWEGLTVDDIKKSTGCDFTVSPKLIPMRQIST

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q24JZ7Q24JZ7_BOVINOXCT1520
A0A3Q1LIX4A0A3Q1LIX4_BOVINOXCT1523
A0A3Q1N4X8A0A3Q1N4X8_BOVINOXCT1486
A0AAA9TEM5A0AAA9TEM5_BOVINOXCT1481
A0AAA9S8Z7A0AAA9S8Z7_BOVINOXCT1492

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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