A0A3Q1LV32 · A0A3Q1LV32_BOVIN
- ProteinSuccinyl-CoA:3-ketoacid-coenzyme A transferase
- GeneOXCT1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids490 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Catalytic activity
- a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
Pathway
Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 344 | 5-glutamyl coenzyme A thioester intermediate | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | succinyl-CoA:3-oxo-acid CoA-transferase activity | |
Biological Process | ketone body catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinyl-CoA:3-ketoacid-coenzyme A transferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0A3Q1LV32
Proteomes
Organism-specific databases
Subcellular Location
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length490
- Mass (Da)53,364
- Last updated2019-04-10 v1
- ChecksumE3D5A3D5AB6DD7BA
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q24JZ7 | Q24JZ7_BOVIN | OXCT1 | 520 | ||
A0A3Q1LIX4 | A0A3Q1LIX4_BOVIN | OXCT1 | 523 | ||
A0A3Q1N4X8 | A0A3Q1N4X8_BOVIN | OXCT1 | 486 | ||
A0AAA9TEM5 | A0AAA9TEM5_BOVIN | OXCT1 | 481 | ||
A0AAA9S8Z7 | A0AAA9S8Z7_BOVIN | OXCT1 | 492 |
Keywords
- Technical term