A0A3Q1LJG6 · A0A3Q1LJG6_BOVIN

  • Protein
    aldehyde oxidase
  • Gene
    AOX1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

Mo-molybdopterin (UniProtKB | Rhea| CHEBI:71302 )

Note: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 2 [2Fe-2S] clusters.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site47[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site52[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site55[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site77[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site117[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site120[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site152[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site154[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site267-274FAD (UniProtKB | ChEBI)
Binding site370FAD (UniProtKB | ChEBI)
Binding site414FAD (UniProtKB | ChEBI)
Binding site432FAD (UniProtKB | ChEBI)
Binding site780Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site811Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site925Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site927substrate
Binding site1092Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Active site1274Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Functionaldehyde oxidase activity
Molecular FunctionFAD binding
Molecular Functioniron ion binding
Molecular Functionmolybdopterin cofactor binding
Molecular FunctionNAD binding
Molecular Functionprotein homodimerization activity
Biological Processlipid metabolic process
Biological Processxenobiotic metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    aldehyde oxidase
  • EC number

Gene names

    • Name
      AOX1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0A3Q1LJG6

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-952Fe-2S ferredoxin-type
Domain239-424FAD-binding PCMH-type

Sequence similarities

Belongs to the xanthine dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,342
  • Mass (Da)
    147,856
  • Last updated
    2024-05-29 v2
  • Checksum
    57F8E59494EFAC38
LSGGAQDLDYTLKRDDLYITEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNPITKKIRHYPANACLTPICSLYGAAVTTVEGIGSTKTRIHPVQERIAKCHGTQCGFCTPGMVMSLYTLLRNHPEPTLTQLNDALGGNLCRCTGYRPIINACKTFCKTSGCCQSKENGVCCLDQGINGLPEFEEGNETSLKLFSEEEFLPLDPTQELIFPPELMTMAEKKTQKTRIFGSDRMTWISPVTLKELLEAKVKYPQAPVVMGNTSVGPDMKFKGIFHPVIISPDRIEELSVVNYTDNGLTLGAAVSLAEVKDILANVTRKLPEEKTQMYHALLKHLETLAGPQIRNMASLGGHIVSRHPDSDLNPLLAVGNCTLNLLSKEGRRQIPLNEQFLRKCPSADLKPEEILISVNIPYSRKWEFVSAFRQAQRQQNALAIVNSGMRVCFGKGDGIIRELSIAYGGVGPTTILANNSCQKLIGRPWNEEMLDAACRLILDEVSLPGSAPGGRVEFKRTLIVSFLFKFYLEVSQILKGMDPVHYPSLASKNESALEDLHSRHYWSTLKYQNADPKQLSQDPVGHPIMHLSGIKHATGEAVYCDDMPVVDRELFLTFVTSSRAHAKIVSIDVSAALSLPGVVDILTGEHLPSITTTFDFLTDADQLLSTDEVSCVGQLVCAVIADSEVQARRAAQQVKIVYQDLEPVILTIEEAIQNKSFFEPERKLEYGNVDEAFKVVDQILEGEIHMGGQEHFYMETQSMLVVPKGEDREIDVYVSAQFPKYIQDITASVLKVSANKVMCHVKRVGGAFGGKVTKTGVLAAITAFAANKHGRPVRCILERGEDILITGGRHPYLGKYKAGFMNDGRILALDMEHYNNAGAFLDESLFVIEMGLLKLENAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLITEACITEVAAKCGLPPEKVRMINMYKEIDQTPYKQEINTKNLTQCWKECMATSSYTLRKAAVEKFNSENYWKKKGLAMVPLKYPIGLGSVAAGQAAALVHIYLDGSVLVTHGGIEMGQGVHTKMIQVASRELRMPLSSIHLRGTSTETIPNTNPSGGSVVADLNGLAVKDACQTLLKRLKPIISKNPKGTWKDWAQAAFNESISLSATGYFRGYESNINWETGEGHPFEYFVYGAACSEVEIDCLTGAHKNIRTDIVMDVGYSINPALDVGQIEGAFIQGMGLYTIEELNYSPQGVLYTRGPNQYKIPAICDIPMELHISFLPPSENSNTLYSSKGLGESGIFLGCSVFFAIHDAIRAARQERGLPGPLRLNSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWSVPI

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0AAA9T2X8A0AAA9T2X8_BOVINAOX11308
F1MRY9F1MRY9_BOVINAOX11339
A0AAA9TN84A0AAA9TN84_BOVINAOX11308
A0AAA9S924A0AAA9S924_BOVINAOX11271

Keywords

Genome annotation databases

Similar Proteins

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