A0A3Q0L6Y4 · A0A3Q0L6Y4_VIBVU
- Proteinlactoylglutathione lyase
- GenegloA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids138 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- (R)-S-lactoylglutathione = glutathione + methylglyoxal
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
Pathway
Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 59 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | ||||
Sequence: E | ||||||
Binding site | 77 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | ||||
Sequence: H | ||||||
Active site | 125 | Proton donor/acceptor | ||||
Sequence: E | ||||||
Binding site | 125 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | lactoylglutathione lyase activity | |
Molecular Function | metal ion binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namelactoylglutathione lyase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio
Accessions
- Primary accessionA0A3Q0L6Y4
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 5-129 | VOC | ||||
Sequence: RILHTMLRVGNLDKSIQFYTEVMGMQLLRTNENKEYEYTLAFLGYGDESQGAVIELTYNWGKTEYDLGSAFGHIAIGVDDIYVTCDAIKAAGGNVTREPGPVKGGTTHIAFVKDPDGYMIELIQN |
Sequence similarities
Belongs to the glyoxalase I family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length138
- Mass (Da)15,087
- Last updated2019-02-13 v1
- ChecksumB399C1159AC3311B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016795 EMBL· GenBank· DDBJ | AAO11423.2 EMBL· GenBank· DDBJ | Genomic DNA |