A0A3P9AWG7 · A0A3P9AWG7_9CICH
- ProteinBeta-glucuronidase
- GeneGUSB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids598 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Plays an important role in the degradation of dermatan and keratan sulfates.
Catalytic activity
- a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol
Activity regulation
Inhibited by L-aspartic acid.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular space | |
Cellular Component | lysosome | |
Molecular Function | beta-glucuronidase activity | |
Molecular Function | carbohydrate binding | |
Biological Process | carbohydrate metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBeta-glucuronidase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Cichlomorphae > Cichliformes > Cichlidae > African cichlids > Pseudocrenilabrinae > Haplochromini > Maylandia > Maylandia zebra complex
Accessions
- Primary accessionA0A3P9AWG7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-24 | ||||
Chain | PRO_5018296981 | 25-598 | Beta-glucuronidase | ||
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 41-225 | Glycosyl hydrolases family 2 sugar binding | |||
Domain | 227-328 | Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich | |||
Domain | 330-413 | Glycoside hydrolase family 2 catalytic | |||
Domain | 417-582 | Glycoside hydrolase family 2 catalytic | |||
Sequence similarities
Belongs to the glycosyl hydrolase 2 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length598
- Mass (Da)68,845
- Last updated2019-02-13 v1
- Checksum668CB86138A2484F
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A3P9AWG2 | A0A3P9AWG2_9CICH | GUSB | 647 |
Keywords
- Technical term