A0A3P8Z3P7 · A0A3P8Z3P7_ESOLU

Function

Catalytic activity

  • 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H+ = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1,3-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-O-(9Z-octadecenyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 13-cis-retinol + hexadecanoyl-CoA = 13-cis-retinyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
    EC:2.3.1.20 (UniProtKB | ENZYME | Rhea)
  • all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA
    This reaction proceeds in the forward direction.
    EC:2.3.1.76 (UniProtKB | ENZYME | Rhea)
  • all-trans-retinol + hexadecanoyl-CoA = all-trans-retinyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • hexadecan-1-ol + hexadecanoyl-CoA = hexadecanyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • hexadecane-1,2-diol + 2 hexadecanoyl-CoA = 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA
    This reaction proceeds in the forward direction.
  • hexadecane-1,2-diol + hexadecanoyl-CoA = 2-hydroxyhexadecyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.

Pathway

Lipid metabolism; glycerolipid metabolism.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site397

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functiondiacylglycerol O-acyltransferase activity
Molecular Functionretinol O-fatty-acyltransferase activity
Biological Processtriglyceride biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-acyltransferase

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Esociformes > Esocidae > Esox

Accessions

  • Primary accession
    A0A3P8Z3P7

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane70-91Helical
Transmembrane111-131Helical
Transmembrane151-168Helical
Transmembrane174-191Helical
Transmembrane305-324Helical
Transmembrane408-425Helical
Transmembrane437-455Helical

Keywords

Expression

Gene expression databases

Interaction

Subunit

Homodimer or homotetramer; both forms have similar enzymatic activities.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    467
  • Mass (Da)
    54,132
  • Last updated
    2020-12-02 v2
  • Checksum
    14422FD3A6BBEB14
QHRHAGQSVTGNVSVHSVRYQRGEFACRCSGHDGGIAPLSNPGSYCILSCHVLQESLLSSASGYRNYRGILNWCVVMLVLSNARLFLENLIKYGILVDPIQVVSLFLKDPYSWPALCLVIVSNVFIMAALYTERRLSVGTISETTGTFLHFVNLTTLLCFPSATVLTLTSMTPVGGVFALGVFTILFLKLYSYKDVNMWCREIRHSNARTLTRSQSCPSVARSNGSAVHAHVSYPGNLTHRDIYYFVLAPTLCYELNFPRSPRIRKSFLLRRLFEMVRSTWMVPTIQNSMKPFQDMDFSRMMERMLKLAVPNHLIWLIFFYWFFHSSMNFVAELLQFGDREFYRDWWNSETVTYFWSNWNIPVHKWCLRHFYQPIMRRGVSKWVARTAVFLLSAFFHEYLVSVPLKMFRLWAFMGMMAQIPLAWFVSRFLRGNYGNAAVWISLIIGQPVAVLMYFHDYYVLHYCAAF

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A6Q2Y023A0A6Q2Y023_ESOLU513
A0A3P8Z3N3A0A3P8Z3N3_ESOLU445
A0A6Q2YA32A0A6Q2YA32_ESOLU472
A0A6Q2Y3A6A0A6Q2Y3A6_ESOLU442
A0A6Q2XGD0A0A6Q2XGD0_ESOLU463
A0A6Q2XEC0A0A6Q2XEC0_ESOLU410
A0A6Q2X8B7A0A6Q2X8B7_ESOLU452
A0A6Q2WYG8A0A6Q2WYG8_ESOLU509
A0A6Q2YHU8A0A6Q2YHU8_ESOLU437

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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