A0A3P8XCL7 · A0A3P8XCL7_ESOLU
- Proteinprotein-tyrosine-phosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids645 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | centrosome | |
Cellular Component | cytoplasm | |
Cellular Component | mitotic spindle | |
Cellular Component | nucleolus | |
Cellular Component | spindle pole | |
Molecular Function | myosin phosphatase activity | |
Molecular Function | protein tyrosine phosphatase activity | |
Biological Process | cilium assembly | |
Biological Process | microtubule cytoskeleton organization | |
Biological Process | positive regulation of cytokinesis | |
Biological Process | regulation of exit from mitosis |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameprotein-tyrosine-phosphatase
- EC number
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Esociformes > Esocidae > Esox
Accessions
- Primary accessionA0A3P8XCL7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 205-362 | Tyrosine-protein phosphatase | ||||
Sequence: DFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFRRHNVTTVVRLNKKIYDAKRFTDAGFDHYDLFFVDGSTPSDVITRRFLHICEITDGAVAVHCKAGLGRTGTLIGCYLMKHYRFTAAEAIAWIRVCRPGSVIGPQQHFLEEKQAAMWLQGD | ||||||
Domain | 287-349 | Tyrosine specific protein phosphatases | ||||
Sequence: RRFLHICEITDGAVAVHCKAGLGRTGTLIGCYLMKHYRFTAAEAIAWIRVCRPGSVIGPQQHF | ||||||
Region | 426-562 | Disordered | ||||
Sequence: LRALKGRRQPRSATTGALRLEEMKLHTRSPSQPFSRMNPGEVTQGTISPLKSSKVPSSPFASATAKRISRNSSSSASNLKSSNSRLASSLGNLYATDGSEDNRKPPYAPSSSPSSTPPSSTVTTSIPPSGRAAGGHG | ||||||
Compositional bias | 453-521 | Polar residues | ||||
Sequence: RSPSQPFSRMNPGEVTQGTISPLKSSKVPSSPFASATAKRISRNSSSSASNLKSSNSRLASSLGNLYAT | ||||||
Compositional bias | 530-553 | Polar residues | ||||
Sequence: PPYAPSSSPSSTPPSSTVTTSIPP | ||||||
Region | 575-632 | Disordered | ||||
Sequence: NNNQYNSSPPGVFGHGGPAVAPHHAAGRSGPGVEEYSSYRPQQGGHAGLSGPSGRYLS |
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length645
- Mass (Da)71,490
- Last updated2019-02-13 v1
- Checksum30292115640EAD80
Computationally mapped potential isoform sequences
There are 8 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A6Q2Y299 | A0A6Q2Y299_ESOLU | 437 | |||
A0A6Q2X612 | A0A6Q2X612_ESOLU | 458 | |||
A0A6Q2YLK7 | A0A6Q2YLK7_ESOLU | 635 | |||
A0A6Q2YLX5 | A0A6Q2YLX5_ESOLU | 530 | |||
A0A6Q2YQG0 | A0A6Q2YQG0_ESOLU | 438 | |||
A0A3P8XCN3 | A0A3P8XCN3_ESOLU | 582 | |||
A0A6Q2YDP5 | A0A6Q2YDP5_ESOLU | 446 | |||
A0A6Q2YIG1 | A0A6Q2YIG1_ESOLU | 524 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 453-521 | Polar residues | ||||
Sequence: RSPSQPFSRMNPGEVTQGTISPLKSSKVPSSPFASATAKRISRNSSSSASNLKSSNSRLASSLGNLYAT | ||||||
Compositional bias | 530-553 | Polar residues | ||||
Sequence: PPYAPSSSPSSTPPSSTVTTSIPP |
Keywords
- Technical term